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  1. Article

    Correction: Corrigendum: Genome-wide characterization of the routes to pluripotency

    Nature 516, 198–206 (2014); doi:10.1038/nature14046 In this Article, the address listed as Nicole Cloonan’s present address (QIMR Berghofer Medical Research Institute, Queensland 4006, Australia) should have b...

    Samer M. I. Hussein, Mira C. Puri, Peter D. Tonge, Marco Benevento… in Nature (2015)

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  2. Article

    Correction: Corrigendum: Divergent reprogramming routes lead to alternative stem-cell states

    Nature 516, 192–197 (2014); doi:10.1038/nature14047 In this Article, the address listed as Nicole Cloonan’s present address (QIMR Berghofer Medical Research Institute, Queensland 4006, Australia) should have b...

    Peter D. Tonge, Andrew J. Corso, Claudio Monetti, Samer M. I. Hussein… in Nature (2015)

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    Article

    Small RNA changes en route to distinct cellular states of induced pluripotency

    MicroRNAs (miRNAs) are critical to somatic cell reprogramming into induced pluripotent stem cells (iPSCs), however, exactly how miRNA expression changes support the transition to pluripotency requires further ...

    Jennifer L. Clancy, Hardip R. Patel, Samer M. I. Hussein… in Nature Communications (2014)

  4. Article

    Open Access

    An epigenomic roadmap to induced pluripotency reveals DNA methylation as a reprogramming modulator

    Reprogramming of somatic cells to induced pluripotent stem cells involves a dynamic rearrangement of the epigenetic landscape. To characterize this epigenomic roadmap, we have performed MethylC-seq, ChIP-seq (...

    Dong-Sung Lee, Jong-Yeon Shin, Peter D. Tonge, Mira C. Puri… in Nature Communications (2014)

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    Article

    Genome-wide characterization of the routes to pluripotency

    Somatic cell reprogramming to a pluripotent state continues to challenge many of our assumptions about cellular specification, and despite major efforts, we lack a complete molecular characterization of the re...

    Samer M. I. Hussein, Mira C. Puri, Peter D. Tonge, Marco Benevento… in Nature (2014)

  6. No Access

    Article

    Divergent reprogramming routes lead to alternative stem-cell states

    Pluripotency is defined by the ability of a cell to differentiate to the derivatives of all the three embryonic germ layers: ectoderm, mesoderm and endoderm. Pluripotent cells can be captured via the archetypa...

    Peter D. Tonge, Andrew J. Corso, Claudio Monetti, Samer M. I. Hussein… in Nature (2014)

  7. Article

    G-quadruplexes regulate Epstein-Barr virus–encoded nuclear antigen 1 mRNA translation

    Biophysical analysis reveals that conserved G-rich sequences within the mRNAs of gammaherpesvirus genome maintenance proteins (GMPs) form G-quadruplexes (G4). Stabilization of mRNA G4 motifs represses GMP tran...

    Pierre Murat, Jie Zhong, Lea Lekieffre, Nathan P Cowieson… in Nature Chemical Biology (2014)

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  8. Article

    The ins and outs of translation

    A report on the 2nd EMBO Conference on Protein Synthesis and Translational Control, Heidelberg, Germany, 12-16 September 2007.

    Jennifer L Clancy, Marco Nousch, Marina Rodnina, Thomas Preiss in Genome Biology (2007)

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  9. No Access

    Article

    EDD, the human orthologue of the hyperplastic discs tumour suppressor gene, is amplified and overexpressed in cancer

    EDD (E3 isolated by differential display), located at chromosome 8q22.3, is the human orthologue of the Drosophila melanogaster tumour suppressor gene ‘hyperplastic discs’ and encodes a HECT domain E3 ubiquitin p...

    Jennifer L Clancy, Michelle J Henderson, Amanda J Russell, David W Anderson… in Oncogene (2003)