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  1. No Access

    Article

    The TRAIL receptor agonist drozitumab targets basal B triple-negative breast cancer cells that express vimentin and Axl

    Previously, we found that GST-tagged tumor necrosis factor-related apoptosis inducing ligand preferentially killed triple-negative breast cancer (TNBC) cells with a mesenchymal phenotype by activating death re...

    Jennifer L. Dine, Ciara C. O’Sullivan… in Breast Cancer Research and Treatment (2016)

  2. Article

    Open Access

    Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening

    Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) binds to its receptors, TRAIL-receptor 1 (TRAIL-R1) and TRAIL-receptor 2 (TRAIL-R2), leading to apoptosis by activation of caspase-8 and the down...

    Sireesha V Garimella, Kristie Gehlhaus, Jennifer L Dine… in Breast Cancer Research (2014)

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