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Article
Continuous Cell Separation Using Microfluidic-Based Cell Retention Device with Alternative Boosted Flow
The development of a continuous process for cell separation is growing rapidly due to the current trend of cost-effective manufacturing in biological industries. The continuous cell separation process has a si...
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Article
Open AccessPlug-and-Play In Vitro Metastasis System toward Recapitulating the Metastatic Cascade
Microfluidic-based tumor models that mimic tumor culture environment have been developed to understand the cancer metastasis mechanism and discover effective antimetastatic drugs. These models successfully rec...
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Article
Open AccessMicrofluidic channel optimization to improve hydrodynamic dissociation of cell aggregates and tissue
Maximizing the speed and efficiency at which single cells can be liberated from tissues would dramatically advance cell-based diagnostics and therapies. Conventional methods involve numerous manual processing ...
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Article
Hollow fiber integrated microfluidic platforms for in vitro Co-culture of multiple cell types
This study demonstrates a rapid prototy** approach for fabricating and integrating porous hollow fibers (HFs) into microfluidic device. Integration of HF can enhance mass transfer and recapitulate tubular sh...
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Article
Formation of enterovirus-like particle aggregates by recombinant baculoviruses co-expressing P1 and 3CD in insect cells
The assembly of enterovirus requires the cleavage of P1 polyprotein by protease 3CD into individual structural proteins. Two recombinant baculoviruses were constructed to encode P1 and 3CD of enterovirus 71 (E...