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  1. Article

    Open Access

    Local delivery of accutox® synergises with immune-checkpoint inhibitors at disrupting tumor growth

    The Accum® platform was initially designed to accumulate biomedicines in target cells by inducing endosomal-to-cytosol escape. Interestingly however, the use of unconjugated Accum® was observed to trigger cell de...

    Jean Pierre Bikorimana, Nehme El-Hachem in Journal of Translational Medicine (2024)

  2. Article

    Open Access

    UM171A-induced ROS promote antigen cross-presentation of immunogenic peptides by bone marrow-derived mesenchymal stromal cells

    Mesenchymal stromal cells (MSCs) have been extensively used in the clinic due to their exquisite tissue repair capacity. However, they also hold promise in the field of cellular vaccination as they can behave ...

    Natasha Salame, Jean-Pierre Bikorimana, Nehme El-Hachem in Stem Cell Research & Therapy (2022)