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Article
Open AccessLocus coeruleus contrast and diffusivity metrics differentially relate to age and memory performance
Neurocognitive aging researchers are increasingly focused on the locus coeruleus, a neuromodulatory brainstem structure that degrades with age. With this rapid growth, the field will benefit from consensus reg...
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Article
Transition and reversal: long-term experience of the MACE procedure in children
Analysis of outcomes and follow-up of children who underwent the Malone antegrade continence enema (MACE) procedure in a UK tertiary paediatric surgery unit.
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Article
Open AccessNeuromelanin detection by magnetic resonance imaging (MRI) and its promise as a biomarker for Parkinson’s disease
The diagnosis of Parkinson’s disease (PD) occurs after pathogenesis is advanced and many substantia nigra (SN) dopamine neurons have already died. Now that therapies to block this neuronal loss are under devel...
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Article
Imaging Parkinsonian Pathology in Substantia Nigra with MRI
The substantia nigra pars compacta (SNc) and its projection to the striatum undergo profound degeneration in Parkinson’s disease (PD). Literature on imaging PD-related changes in the nigrostriatal system using...
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Article
Improved Neuroimaging Atlas of the Dentate Nucleus
The dentate nucleus (DN) of the cerebellum is the major output nucleus of the cerebellum and is rich in iron. Quantitative susceptibility map** (QSM) provides better iron-sensitive MRI contrast to delineate ...
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Article
Reproducibility of locus coeruleus and substantia nigra imaging with neuromelanin sensitive MRI
The purpose of this study was to assess the reproducibility of substantia nigra pars compacta (SNpc) and locus coeruleus (LC) delineation and measurement with neuromelanin-sensitive MRI.
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Article
Open AccessThe reproducibility of measurements of intramuscular magnesium concentrations and muscle oxidative capacity using 31P MRS
31P magnetic resonance spectroscopy (31P MRS) has been used to measure intramuscular magnesium concentrations and muscle metabolism. Abnormal intramuscular magnesium has been reported in several patient populatio...
