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  1. Article

    Open Access

    Mitochondrial DNA copy number can influence mortality and cardiovascular disease via methylation of nuclear DNA CpGs

    Mitochondrial DNA copy number (mtDNA-CN) has been associated with a variety of aging-related diseases, including all-cause mortality. However, the mechanism by which mtDNA-CN influences disease is not currentl...

    Christina A. Castellani, Ryan J. Longchamps, Jason A. Sumpter in Genome Medicine (2020)