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Article
Open AccessGenome evolution in the allotetraploid frog Xenopus laevis
To explore the origins and consequences of tetraploidy in the African clawed frog, we sequenced the Xenopus laevis genome and compared it to the related diploid X. tropicalis genome. We characterize the allotetra...
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Article
Open AccessA whole-genome shotgun approach for assembling and anchoring the hexaploid bread wheat genome
Polyploid species have long been thought to be recalcitrant to whole-genome assembly. By combining high-throughput sequencing, recent developments in parallel computing, and genetic map**, we derive, de novo, a...
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Article
Open AccessAssemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species
The process of generating raw genome sequence data continues to become cheaper, faster, and more accurate. However, assembly of such data into high-quality, finished genome sequences remains challenging. Many ...
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Article
Open AccessInsights into bilaterian evolution from three spiralian genomes
Comparative analysis of the genomes of one mollusc (Lottia gigantea) and two annelids (Capitella teleta and Helobdella robusta) enable a more complete reconstruction of genomic features of the last common ancesto...
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Article
Open AccessThe dynamic genome of Hydra
Hydra, first described by Anton van Leeuwenhoek in a letter to the Royal Society in 1702, has been studied by biologists for centuries and now is an important model for work on axial patterning, stem cell biology...
