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  1. Article

    Open Access

    Loop-extruders alter bacterial chromosome topology to direct entropic forces for segregation

    Entropic forces have been argued to drive bacterial chromosome segregation during replication. In many bacterial species, however, specifically evolved mechanisms, such as loop-extruding SMC complexes and the ...

    Janni Harju, Muriel C. F. van Teeseling, Chase P. Broedersz in Nature Communications (2024)

  2. Article

    Open Access

    Publisher Correction: Nonlinear mechanics of human mitotic chromosomes

    Anna E. C. Meijering, Kata Sarlós, Christian F. Nielsen, Hannes Witt, Janni Harju in Nature (2022)

  3. Article

    Open Access

    Nonlinear mechanics of human mitotic chromosomes

    In preparation for mitotic cell division, the nuclear DNA of human cells is compacted into individualized, X-shaped chromosomes1. This metamorphosis is driven mainly by the combined action of condensins and topoi...

    Anna E. C. Meijering, Kata Sarlós, Christian F. Nielsen, Hannes Witt, Janni Harju in Nature (2022)