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  1. No Access

    Article

    Production of antifungal lipopeptide from Bacillus subtilis in submerged fermentation using shake flask and fermentor

    Optimization of the production of antifungal lipopeptide, iturin A, by B. subtilis was carried out in submerged cultural fermentation. In a shake-flask experiment, response surface methodology (RSM) was employed ...

    Ing-Lung Shih, Chih-Yang Lin, Jane-Yii Wu… in Korean Journal of Chemical Engineering (2009)

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    Article

    Using Redox Potential to Detect Microbial Activities During Clavulanic Acid Biosynthesis in Streptomyces clavuligerus

    Production of clavulanic acid (CA) by Streptomyces clavuligerus in a shake-flask culture increased from 92 to 180 mg l−1 with an increased O2 transfer efficiency (0.039 → 0.058 s−1), which maintained the redox po...

    Yun-Huin Lin, Sz-Chwun John Hwang, Jian Tong Gong, Jane-Yii Wu… in Biotechnology Letters (2005)