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    Isolation of a Novel Morphinan 3-O-Diglucuronide Metabolite from Dog Urine

    Following oral administration of the narcotic antagonist nalmefene [17-(cyclopropyl-methyl)-4,5α-epoxy-6-methylenemorphinan-3,14-diol] labeled with 14C to the dog, approximately 50% of the dose was excreted in th...

    Ross Dixon, Jane Hsiao, Hon-Bin Hsu, Maciej Smulkowski… in Pharmaceutical Research (1989)