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  1. Article

    Open Access

    B-lymphocyte stimulator/a proliferation-inducing ligand heterotrimers are elevated in the sera of patients with autoimmune disease and are neutralized by atacicept and B-cell maturation antigen-immunoglobulin

    B-lymphocyte stimulator (BLyS) and a proliferation-inducing ligand (APRIL) are members of the tumor necrosis factor (TNF) family that regulate B-cell maturation, survival, and function. They are overexpressed ...

    Stacey R Dillon, Brandon Harder, Kenneth B Lewis… in Arthritis Research & Therapy (2010)

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  2. No Access

    Chapter

    Non-Receptor Protein Tyrosine Kinases

    Reversible phosphorylation of proteins has proved to be the most widely-employed regulatory mechanism governing cell behavior. Seminal studies performed in the 1960s by Edwin Krebs and colleagues on the regula...

    Roger M. Perlmutter, Steven J. Anderson… in Normal and Malignant Hematopoiesis (1995)