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  1. Article

    Open Access

    Inhibition of epigenetic and cell cycle-related targets in glioblastoma cell lines reveals that onametostat reduces proliferation and viability in both normoxic and hypoxic conditions

    The choice of targeted therapies for treatment of glioblastoma patients is currently limited, and most glioblastoma patients die from the disease recurrence. Thus, systematic studies in simplified model system...

    Darja Lavogina, Mattias Kaspar Krõlov, Hans Vellama… in Scientific Reports (2024)

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  2. Article

    Open Access

    Viability fingerprint of glioblastoma cell lines: roles of mitotic, proliferative, and epigenetic targets

    Despite the use of multimodal treatment combinations, the prognosis of glioblastoma (GB) is still poor. To prevent rapid tumor recurrence, targeted strategies for the treatment of GB are widely sought. Here, w...

    Darja Lavogina, Tõnis Laasfeld, Markus Vardja, Helen Lust, Jana Jaal in Scientific Reports (2021)

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