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  1. Article

    Open Access

    A chromosome-scale reference genome for Spironucleus salmonicida

    Spironucleus salmonicida is a diplomonad causing systemic infection in salmon. The first S. salmonicida genome assembly was published 2014 and has been a valuable reference genome in protist research. However, th...

    Feifei Xu, Alejandro Jiménez-González, Zeynep Kurt, Ásgeir Ástvaldsson in Scientific Data (2022)

  2. No Access

    Article

    Organelles that illuminate the origins of Trichomonas hydrogenosomes and Giardia mitosomes

    Many anaerobic microbial parasites possess highly modified mitochondria known as mitochondrion-related organelles (MROs). The best-studied of these are the hydrogenosomes of Trichomonas vaginalis and Spironucleus...

    Michelle M. Leger, Martin Kolisko, Ryoma Kamikawa in Nature Ecology & Evolution (2017)

  3. Article

    Open Access

    Erratum to: On the reversibility of parasitism: adaptation to a free-living lifestyle via gene acquisitions in the diplomonad Trepomonas sp. PC1

    Feifei Xu, Jon Jerlström-Hultqvist, Martin Kolisko, Alastair G. B. Simpson in BMC Biology (2016)

  4. Article

    Open Access

    On the reversibility of parasitism: adaptation to a free-living lifestyle via gene acquisitions in the diplomonad Trepomonas sp. PC1

    It is generally thought that the evolutionary transition to parasitism is irreversible because it is associated with the loss of functions needed for a free-living lifestyle. Nevertheless, free-living taxa are...

    Feifei Xu, Jon Jerlström-Hultqvist, Martin Kolisko, Alastair G. B. Simpson in BMC Biology (2016)

  5. Article

    Open Access

    Hydrogenosomes in the diplomonad Spironucleus salmonicida

    Acquisition of the mitochondrion is a key event in the evolution of the eukaryotic cell, but diversification of the organelle has occurred during eukaryotic evolution. One example of such mitochondria-related ...

    Jon Jerlström-Hultqvist, Elin Einarsson, Feifei Xu, Karin Hjort in Nature Communications (2013)

  6. Article

    Open Access

    Genome analysis and comparative genomics of a Giardia intestinalis assemblage E isolate

    Giardia intestinalis is a protozoan parasite that causes diarrhea in a wide range of mammalian species. To further understand the genetic diversity between the Giardia intestinalis species, we have performed geno...

    Jon Jerlström-Hultqvist, Oscar Franzén, Johan Ankarklev, Feifei Xu in BMC Genomics (2010)

  7. Article

    Open Access

    Large genomic differences between the morphologically indistinguishable diplomonads Spironucleus barkhanus and Spironucleus salmonicida

    Microbial eukaryotes show large variations in genome structure and content between lineages, indicating extensive flexibility over evolutionary timescales. Here we address the tempo and mode of such changes wi...

    Katarina Roxström-Lindquist, Jon Jerlström-Hultqvist, Anders Jørgensen in BMC Genomics (2010)

  8. No Access

    Protocol

    Horizontal Gene Transfer Between Microbial Eukaryotes

    Comparative genomics have identified two loosely defined classes of genes: widely distributed core genes that encode proteins for central functions in the cell and accessory genes that are patchily distributed...

    Jan O. Andersson in Horizontal Gene Transfer (2009)

  9. Article

    Open Access

    A genomic survey of the fish parasite Spironucleus salmonicida indicates genomic plasticity among diplomonads and significant lateral gene transfer in eukaryote genome evolution

    Comparative genomic studies of the mitochondrion-lacking protist group Diplomonadida (diplomonads) has been lacking, although Giardia lamblia has been intensively studied. We have performed a sequence survey proj...

    Jan O Andersson, Åsa M Sjögren, David S Horner, Colleen A Murphy in BMC Genomics (2007)

  10. Article

    Open Access

    Evolution of four gene families with patchy phylogenetic distributions: influx of genes into protist genomes

    Lateral gene transfer (LGT) in eukaryotes from non-organellar sources is a controversial subject in need of further study. Here we present gene distribution and phylogenetic analyses of the genes encoding the ...

    Jan O Andersson, Robert P Hirt, Peter G Foster, Andrew J Roger in BMC Evolutionary Biology (2006)

  11. Article

    Open Access

    Evolution of glutamate dehydrogenase genes: evidence for lateral gene transfer within and between prokaryotes and eukaryotes

    Lateral gene transfer can introduce genes with novel functions into genomes or replace genes with functionally similar orthologs or paralogs. Here we present a study of the occurrence of the latter gene replac...

    Jan O Andersson, Andrew J Roger in BMC Evolutionary Biology (2003)

  12. No Access

    Article

    The genome sequence of Rickettsia prowazekii and the origin of mitochondria

    We describe here the complete genome sequence (1,111,523 base pairs) of the obligate intracellular parasite Rickettsia prowazekii, the causative agent of epidemic typhus. This genome contains 834 protein-coding g...

    Siv G. E. Andersson, Alireza Zomorodipour, Jan O. Andersson in Nature (1998)