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  1. No Access

    Article

    A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation

    Robert Jenkins and colleagues report fine map** of the glioma risk region at 8q24.21. They identify a new low-frequency variant in the region that is strongly associated with risk of oligodendroglial tumors ...

    Robert B Jenkins, Yuanyuan **ao, Hugues Sicotte, Paul A Decker… in Nature Genetics (2012)

  2. No Access

    Article

    Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility

    Margaret Wrensch and colleagues report a genome-wide association and replication study for high-grade glioma. They show that common variants in the CDKN2B and RTEL1 regions are associated with risk of this aggres...

    Margaret Wrensch, Robert B Jenkins, Jeffrey S Chang, Ru-Fang Yeh… in Nature Genetics (2009)

  3. No Access

    Article

    The role of chemotherapy in the treatment of patients with brain metastases from solid tumors

    Chemotherapy for brain metastases has been considered ineffective because the drugs do not penetrate the intact blood brain barrier. Alternate explanations for past failures of chemotherapy include observation...

    Jan C. Buckner in Cancer and Metastasis Reviews (1991)