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Article
Open AccessThe risks of advancing parental age on neonatal morbidity and mortality are U- or J-shaped for both maternal and paternal ages
The biologic implications of delayed parenthood have been blamed for a major public health crisis in the United States, that includes high rates of neonatal morbidity and mortality (NMM). The objective of this...
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Article
Assessment of dissolved organic carbon and iron effects on water color between a forest and pasture-dominated fine-scale catchment in a Central Appalachian region, West Virginia
Dissolved organic carbon (DOC) and iron (Fe) have been observed to be the important contributors to surface water brownification. Additionally, the DOC quality influences water color by forming Fe-DOC complexe...
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Article
Open AccessEstimating racial health disparities among adverse birth outcomes as deviations from the population rates
Despite significant research, the reasons for racial health disparities among adverse birth outcomes (ABO) remain largely unknown. The bulk of research into racial health disparities among ABO in the United St...
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Article
Open AccessDisentangling the roles of maternal and paternal age on birth prevalence of Down syndrome and other chromosomal disorders using a Bayesian modeling approach
Multiple neonatal and pediatric disorders have been linked to older paternal ages. Combining these findings with the evidence that many men are having children at much later ages generates considerable public ...
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Article
Open AccessAn evaluation of whether a gestational weight gain of 5 to 9 kg for obese women optimizes maternal and neonatal health risks
Maternal obesity has a wide range of health effects on both the pregnant woman and develo** fetus. The clinical significance of these disorders, combined with a dramatically increasing prevalence of obesity ...
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Article
Effect of intra-ovarian injection of mesenchymal stem cells in aged mares
This study aims to determine if intra-ovarian injection of bone marrow–derived mesenchymal stem cells (MSCs) improves or restores ovarian function in aged females.
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Article
Open AccessMetronidazole for the treatment of Tritrichomonas foetus in bulls
Tritrichomonas foetus is a sexually transmitted protozoon that causes reproductive failure, among cattle, so disruptive that many western US states have initiated control prog...
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Chapter
Some Challenges on Quantifying Soil Property Predictions Uncertainty for the GlobalSoilMap Using Legacy Data
The GlobalSoilMap project aims to create digital soil property maps in a raster format for six standard depths (0–5; 5–15; 15–30; 30–60; 60–100; 100–200 cm) and, for the first time, with estimates of uncertainty ...
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Article
Open AccessEvaluating geostatistical modeling of exceedance probability as the first step in disease cluster investigations: very low birth weights near toxic Texas sites
The first step in evaluating potential geographic clusters of disease calls for an evaluation of the disease risk comparing the risk in a defined location to the risk in neighboring locations. Environmental ex...
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Article
Autologous Regulatory T Cells for the Treatment of Type 1 Diabetes
The immune system is tasked with defending the host from a wide array of pathogens and environmental insults. When uncontrolled, this endeavor may lead to off-target reactivity to self-tissues resulting in mul...
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Article
Geostatistical analysis of DNA damage in oysters, Crassostrea virginica, in Lavaca Bay, Texas
This study evaluated the health of the marine ecosystem in Lavaca Bay, Texas using the Eastern oyster (Crassostrea virginica) as the sentinel species. Lavaca Bay has a history of having gradients of concentration...
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Article
Geostatistical analysis of biomarkers of genotoxicity in cattle, Bos taurus and Bos taurus × Bos indicus, sentinels near industrial facilities
This study, performed at the behest of ranchers living and working down-prevailing wind from industrial facilities located in Calhoun County, Texas investigated locational risks to ecosystem health associated ...
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Article
Lung cancer patients’ CD4+ T cells are activated in vitro by MHC II cell-based vaccines despite the presence of myeloid-derived suppressor cells
Advanced non-small cell lung cancer (NSCLC) remains an incurable disease. Immunotherapies that activate patients’ T cells against resident tumor cells are being developed; however, these approaches may not be ...
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Article
Open AccessGeographic risk modeling of childhood cancer relative to county-level crops, hazardous air pollutants and population density characteristics in Texas
Childhood cancer has been linked to a variety of environmental factors, including agricultural activities, industrial pollutants and population mixing, but etiologic studies have often been inconclusive or inc...
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Article
The absence of invariant chain in MHC II cancer vaccines enhances the activation of tumor-reactive type 1 CD4+ T lymphocytes
Activation of tumor-reactive T lymphocytes is a promising approach for the prevention and treatment of patients with metastatic cancers. Strategies that activate CD8+ T cells are particularly promising because of...
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Article
An evaluation of spatial and multivariate covariance among childhood cancer histotypes in Texas (United States)
Spatial modeling of rare diseases, such as childhood cancer, has been hampered by imprecise risk estimates. Recent developments in Bayesian hierarchical modeling include the ability to adjust a disease risk es...
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Article
Landscape Modeling of In Situ Soil Respiration in a Forested Watershed of Southeastern Kentucky, USA
Data on carbon fluxes such as soil respiration are needed to develop strategies for increased carbon sequestration and reduced levels of atmospheric trace gases. Soil respiration is driven by proximal factors ...
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Article
Landscape Influences on Potential Soil Respiration Rates in a Forested Watershed of Southeastern Kentucky
Soil respiration measurements conducted in the laboratory have been shown to be related to temperature and moisture, with maximum rates at soil temperatures between 25 and 40°C and soil moisture between −0.01 ...
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Article
Laboratory comparison of soil redox conditions between red soils and brown soils in Minnesota, USA
Certain soil morphological characteristics create significant problems for hydric soil identification due to lack of commonly observable Fe-based redoximorphic features that indicate seasonally saturated and r...
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Chapter
Perceptions of the Soviet Union and the Arms Race: A Ten Nation Cross-Cultural Study
The image of the enemy is only one component in the behavioral chain which leads to war. Without a negative view of the opponent it is hard to motivate people to commit violent acts. The evidence suggests that...
