6 Result(s)

Article

Identifying biases and their potential solutions in human microbiome studies

Advances in DNA sequencing technology have vastly improved the ability of researchers to explore the microbial inhabitants of the human body. Unfortunately, while these studies have uncovered the importance of...

Jacob T. Nearing, André M. Comeau, Morgan G. I. Langille in Microbiome (2021)

Article

Microbiome differential abundance methods produce different results across 38 datasets

Identifying differentially abundant microbes is a common goal of microbiome studies. Multiple methods are used interchangeably for this purpose in the literature. Yet, there are few large-scale studies systema...

Jacob T. Nearing, Gavin M. Douglas, Molly G. Hayes… in Nature Communications (2022)

Article

Author Correction: Microbiome differential abundance methods produce different results across 38 datasets

Jacob T. Nearing, Gavin M. Douglas, Molly G. Hayes… in Nature Communications (2022)

Article

Investigating the oral microbiome in retrospective and prospective cases of prostate, colon, and breast cancer

The human microbiome has been proposed as a potentially useful biomarker for several cancers. To examine this, we made use of salivary samples from the Atlantic Partnership for Tomorrow’s Health (PATH) project...

Jacob T. Nearing, Vanessa DeClercq, Morgan G. I. Langille in npj Biofilms and Microbiomes (2023)

Article

Oral microbial signatures associated with age and frailty in Canadian adults

This study aimed to assess the association between the oral microbiome, age, and frailty. Data and saliva samples were obtained from male and female participants aged 35–70 years (n = 1357). Saliva samples wer...

Vanessa DeClercq, Robyn J. Wright, Jacob T. Nearing… in Scientific Reports (2024)