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  1. Article

    SSRI Augmentation by 5-Hydroxytryptophan Slow Release: Mouse Pharmacodynamic Proof of Concept

    Drugs, notably SSRIs, that elevate brain extracellular 5-HT (5-HTExt) are antidepressants. Unfortunately, most patients fail to remit. Multipronged clinical evidence suggests that elevating 5-HTExt beyond the SSR...

    Jacob PR Jacobsen, Meghan L Rudder, Wendy Roberts… in Neuropsychopharmacology (2016)

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