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    Effect of Concentrated Urea Solutions on the Infectivity and Hæmagglutinin of Vaccinia Virus

    DURING preliminary experiments attempting to extract deoxyribonucleic acid from vaccinia virus by various physical and chemical means, we incidentally observed that after exposure to 8 M urea the infectious prope...

    J. F. McCREA, JEAN O'LOUGHLIN in Nature (1959)