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  1. Article

    Open Access

    NLRP1 mutations cause autoinflammatory diseases in human

    S Grandemange, E Sanchez, P Louis-Plence, C Rittore, JC Reed… in Pediatric Rheumatology (2015)

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  2. No Access

    Article

    Expression of Bcl-2-related genes in normal and AML progenitors: changes induced by chemotherapy and retinoic acid

    The expression of Bcl-2 family members was examined in normal and leukemic hematopoietic cells. Immature hematopoietic progenitor cells (CD34+/33−/13−) did not express Bcl-2 but Bcl-XL, the majority of CD34 cells...

    M Andreeff, S Jiang, X Zhang, M Konopleva, Z Estrov, VE Snell, Z **e, MF Okcu… in Leukemia (1999)

  3. No Access

    Article

    A multivariate analysis of tumour biological factors predicting response to cytotoxic treatment in advanced breast cancer

    The study was designed to identify factors that could predict response to chemotherapy in breast cancer. A total of 173 patients with measurable or evaluable metastatic breast cancer were enrolled in a randomi...

    J Sjöström, S Krajewski, K Franssila, E Niskanen, V-M Wasenius… in British Journal of Cancer (1998)

  4. No Access

    Article

    A sequential treatment regimen with melatonin and all-trans retinoic acid induces apoptosis in MCF-7 tumour cells

    Neoplastic events are marked by uncontrolled cell proliferation. One major focus of cancer research has been to identify treatments that reduce or inhibit cell growth. Over the years, various compounds, both n...

    KM Eck, L Yuan, L Duffy, PT Ram, S Ayettey, I Chen, CS Cohn… in British Journal of Cancer (1998)

  5. No Access

    Article

    Co-expression of several molecular mechanisms of multidrug resistance and their significance for paclitaxel cytotoxicity in human AML HL-60 cells

    Overexpression of P-glycoprotein (PGP), MRP or LRP has been characterized as the ‘proximal’, while overexpression of the anti-apoptosis Bcl-2 or Bcl-xL relative to the pro-apoptosis Bax protein has been recognize...

    Y Huang, AM Ibrado, JC Reed, G Bullock, S Ray, C Tang, K Bhalla in Leukemia (1997)

  6. No Access

    Article

    Spontaneous overexpression of the long form of the Bcl-X protein in a highly resistant P388 leukaemia

    A novel resistant variant of murine P388 leukaemia, P388/SPR, was identified by de novo resistance to doxorubicin (DOX) in vivo. This mutant displayed a similar level of cross-resistance to etoposide (VP-16) a...

    J-S Kühl, S Krajewski, GE Durán, JC Reed, BI Sikic in British Journal of Cancer (1997)