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Article
Frequencies of KIT and PDGFRA mutations in the MolecGIST prospective population-based study differ from those of advanced GISTs
Gastrointestinal stromal tumors (GISTs) are the most common human sarcoma. Most of the data available on GISTs derive from retrospective studies of patients referred to oncology centers. The MolecGIST study so...
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Chapter
Gastrointestinal stromal tumours
Gastrointestinal stromal tumours (GIST) are rare mesenchymal tumours derived from the interstitial cells of Cajal. Mutations in the KIT gene leading to a constitutively activated KIT receptor protein are the m...
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Article
Dendritic cells are essential for priming but inefficient for boosting antitumour immune response in an orthotopic murine glioma model
The prognosis of malignant gliomas remains dismal and alternative therapeutic strategies are required. Immunotherapy with dendritic cells (DCs) pulsed with tumour antigens emerges as a promising approach. Many...
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Article
Research controversies in management of oral mucositis
The management of mucositis is the subject of many controversies, and the optimal treatment is still not known. Several evaluation scoring systems have been described, but no one of these is appropriate to al...
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Article
Assessment of osteosarcoma response to neoadjuvant chemotherapy: comparative usefulness of dynamic gadolinium-enhanced spin-echo magnetic resonance imaging and technetium-99 m skeletal angioscintigraphy
The aim of this work was to study and compare the usefulness of dynamic contrast-enhanced spin-echo MR imaging with high temporal resolution hydroxymethylene diphosphonate technetium-99 m skeletal angioscinti...
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Article
High-dose chemotherapy with hematopoietic stem cell transplantation in patients with mantle cell or diffuse centrocytic non-Hodgkin’s lymphomas: a single center experience on 18 patients
Between 1985 and 1996, 18 patients with diffuse centrocytic lymphoma (DCL), including nine patients with an established histological and phenotypic diagnosis of mantle cell lymphoma (MCL), received 19 courses ...
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Chapter
Interleukin 10 and non Hodgkin’s lymphomas
Interleukin 10 (IL- 10) is a pleiotropic cytokine which plays a central role in several physiological and pathological processes, in particular in infectious diseases and cancer. IL-10 was initially described ...
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Chapter and Conference Paper
Interleukin-2 Therapy: Report on 129 Patients and Three Different Schedules
Approximately one-half of patients with renal carcinoma develop metastases, and these have a median survival of 8 months [6, 11, 12]. Metastatic renal cancer has been considered for the past 20 years as a tumo...