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  1. No Access

    Chapter

    Unique Vascular Benefits of Estetrol, a Native Fetal Estrogen with Specific Actions in Tissues (NEST)

    Estrogens (E), in oral contraceptives (COCs) and hormone replacement therapy (HRT) drugs used for the relief of climacteric symptoms of menopause, increase the synthesis of clotting factors, decrease the level...

    J. M. Foidart, U. Gaspard, C. Pequeux in Sex Steroids' Effects on Brain, Heart and … (2019)

  2. No Access

    Article

    Estrogènes et fonction vésicale

    L’objectif de cette étude est de décrire l’impact des estrogènes sur la fonction vésicale. Les récepteurs aux estrogènes sont exprimés au niveau du dôme et du trigone vésical et au niveau du système nerveux ce...

    X. Gamé, J. -F. Arnal, P. Rischmann, B. Malavaud in Pelvi-périnéologie (2007)

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    Chapter and Conference Paper

    Estradiol Action in Atherosclerosis and Reendothelialization

    Whereas hormonal replacement/menopause therapy (HRT) in postmenopausal women increases coronary artery disease risk, epidemiological studies (protection in premenopaused women) suggest and experimental studies...

    J.- F. Arnal, H. Laurell, F. Lenfant, V. Douin-Echinard in Tissue-Specific Estrogen Action (2007)

  4. No Access

    Chapter and Conference Paper

    Estrogens and Atherosclerosis

    Numerous epidemiological studies suggest that estrogens protect women against cardiovascular diseases before the age of menopause. After menopause, the cardiovascular risk of women becomes progressively closer...

    F. Bayard, P. Gourdy, R. Elhage, L. Brouchet in New Molecular Mechanisms of Estrogen Actio… (2004)

  5. Article

    Inhaled and exhaled nitric oxide

    Inhaled nitric oxide (NO) is used to treat various cardiopulmonary disorders associated with pulmonary hypertension. The rationale is based on the fact that NO, given by inhalation, only dilates those pulmona...

    B. Thébaud, J.-F. Arnal, J. C. Mercier in Cellular and Molecular Life Sciences CMLS (1999)

  6. No Access

    Article

    Endothelium-derived nitric oxide and vascular physiology and pathology

    In 1980, Furchgott and Zawadzki demonstrated that the relaxation of vascular smooth muscle cells in response to acetylcholine is dependent on the anatomical integrity of the endothelium. Endothelium-derived r...

    J.-F. Arnal, A.-T. Dinh-Xuan, M. Pueyo in Cellular and Molecular Life Sciences CMLS (1999)

  7. Article

    Insulin secretion in rats with chronic nitric oxide synthase blockade

    Nitric oxide, which is produced from l-arginine by a nitric oxide-synthase enzyme, has been shown to be a ubiquitous messenger molecule. Recently, it has been suggested that nitric oxide might influence insulin s...

    Dr. M. E. Pueyo, W. Gonzalez, E. Pussard, J. F. Arnal in Diabetologia (1994)