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  1. Article

    Open Access

    Scheduling nab-paclitaxel combined with gemcitabine as first-line treatment for metastatic pancreatic adenocarcinoma

    Nab-paclitaxel plus gemcitabine (nabP+gemcitabine) offers modest survival gains for patients with metastatic pancreatic ductal adenocarcinoma (PDAC). Sequential scheduling of nabP+gemcitabine in a PDAC mouse m...

    P. G. Corrie, W. Qian, B. Basu, J. W. Valle, S. Falk, C. lwuji… in British Journal of Cancer (2020)

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  2. No Access

    Article

    Sentinel node biopsy in papillary thyroid cancer—what is the potential?

    Sentinel node biopsy (SNB) may identify lymph node metastases in patients with papillary thyroid cancer (PTC), enabling selective application of central node dissection (CND). The aim of this study was to asse...

    S. P. Balasubramanian, J. Brignall, H. Y. Lin… in Langenbeck's Archives of Surgery (2014)

  3. No Access

    Article

    Bulgeless dwarf galaxies and dark matter cores from supernova-driven outflows

    Observations show most dwarf galaxies to be almost 'bulgeless', consisting of a rotating stellar disc embedded in a massive near-constant-density core halo of cold dark matter. This sits uncomfortably with the...

    F. Governato, C. Brook, L. Mayer, A. Brooks, G. Rhee, J. Wadsley, P. Jonsson… in Nature (2010)

  4. No Access

    Article

    Early gas strip** as the origin of the darkest galaxies in the Universe

    Dwarf spheroidal galaxies are dominated by dark matter, and within their ranks Draco, Ursa Minor and Andromeda X are 'darkest'. None of the models so far proposed to explain their formation can account for bot...

    L. Mayer, S. Kazantzidis, C. Mastropietro, J. Wadsley in Nature (2007)

  5. No Access

    Chapter and Conference Paper

    Multi-Scale Simulations of Merging Galaxies with Supermassive Black Holes

    We present the results of the first multi-scale N-body+hydrodynamical simulations of merging galaxies containing central supermassive black holes (SMBHs) and having a spatial resolution of only a few parsecs. ...

    L. Mayer, S. Kazantzidis, P. Madau, M. Colpi… in Relativistic Astrophysics Legacy and Cosmo… (2007)

  6. No Access

    Chapter and Conference Paper

    The Effect of Gaseous Dissipation on the Fate of Supermassive Black Holes in Merging Galaxies

    We analyze the effect of dissipation on the orbital evolution of supermassive black holes (SMBHs) using high-resolution gasdynamical simulations of binary equal- and unequal-mass mergers of disk dominated gala...

    S. Kazantzidis, L. Mayer, M. Colpi, P. Madau… in Growing Black Holes: Accretion in a Cosmol… (2005)