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  1. No Access

    Article

    Galectin-Expression an urologischen Tumoren

    Galectine sind eine Gruppe von 15 Proteinen, die sowohl intra- als auch extrazellulär an bestimmte Kohlenhydratreste binden können und dabei eine wichtige Rolle bei der Regulation des Zellzyklus spielen. So wu...

    S. Waalkes, PD Dr. A.S. Merseburger, A. Simon, J. Serth, M.A. Kuczyk in Der Urologe (2010)

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    Article

    Expression des „Corticotropin releasing faktor rezeptors 2“ (CRFR2) in der humanen Prostata

    Die Expression von Urocortin (Ucn), ein aus 40 Aminosäuren bestehendes Neuropeptid, wurde im Prostatagewebe von Patienten mit BPH berichtet. In verschiedenen Organen ist Ucn bei der Regulation von lokalen Entz...

    Dr. H. Tezval, A.S. Merseburger, M. Seidler, J. Serth, M.A. Kuczyk, M. Oelke in Der Urologe (2008)

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    Article

    Nachweis hypermethylierter Genpromotoren zur Diagnostik des Prostatakarzinoms

    T. Eilers, S. Machtens, H. Tezval, C. Blaue, R. Lichtinghagen, J. Hagemann… in Der Urologe (2007)

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    Article

    Expressionscharakterisierung von Zellzyklusproteinen im Nierenzellkarzinom zur Identifizierung molekularer Prognostikatoren

    J. Serth in Der Urologe (2007)

  5. No Access

    Article

    Positron emission tomography (PET) in the urooncological evaluation of the small pelvis

    Positron emission tomography (PET) with the use of (18F)2-fluoro-d-2-desoxyglucose (FDG) has been investigated to be a highly sensitive and specific imaging modality in the diagnostic of primary and recurrent tum...

    S. Machtens, J. Serth, A. Meyer, C. Kleinhorst, K.-J. Ommer… in World Journal of Urology (2007)

  6. No Access

    Article

    Tissue microarrays: applications in urological cancer research

    Tissue microarrays (TMAs) are used to simultaneously study the expression of proteins in hundreds of tissue samples, offering the important advantage to screen large tissue banks for biomarker expression and t...

    A. S. Merseburger, A. G. Anastasiadis, J. Hennenlotter… in World Journal of Urology (2006)

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    Article

    Correlation of bFGF expression in renal cell cancer with clinical and histopathological features by tissue microarray analysis and measurement of serum levels

    The prognostic value of bFGF for surgically treated renal cell cancer (RCC) patients was evaluated by immunohistochemistry (IHC) and the tissue microarray technique (TMA). Additionally, preoperative serum bFGF...

    M. Horstmann, A. S. Merseburger… in Journal of Cancer Research and Clinical On… (2005)

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    Article

    New aspects on the identification of genetic alterations and prognostically important biological parameters in renal cell cancer

    The observation of extremely variable clinical courses for patients with renal cell carcinomas of an identical pathological stage as well as a comparable histological differentiation resp. growth pattern stron...

    S. Machtens, M. Kuczyk, A. J. Becker, C. Bokemeyer, J. Serth, U. Jonas in Der Urologe (1999)

  9. No Access

    Article

    Detection of p53 tumor-suppressor-gene protein in bladder tumors and prostate cancer: possible clinical implications

    For a variety of human malignancies such as breast cancer and cancer of the prostate, p53 oncoprotein overexpression indicating an alteration of the p53 tumorsuppressor gene has been described as a prognostic fac...

    M. A. Kuczyk, J. Serth, C. Hervatin, H. Arndt, L. Derendorf… in World Journal of Urology (1994)