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  1. No Access

    Chapter and Conference Paper

    Corticosteroid Dependence of Continuous Hemopoiesis In Vitro with Murine or Human Bone Marrow

    Continuous mouse bone marrow cultures (Dexter and Testa 1977) have been used to study in vitro normal marrow hemopoiesis and viral or chemical leukemogenesis (Dexter et al. 1977; Greenberger 1978; Greenberger ...

    H. M. Greenberg, L. M. Parker, P. E. Newburger… in Modern Trends in Human Leukemia IV (1981)

  2. No Access

    Chapter

    Biochemical Purification of a CSF-1 like Molecule Released during Malignant Transformation of IL-3 Dependent Hematopoietic Progenitor cell lines Cocultivated with Gamma Irradiated Clonal Marrow Stromal cell lines

    Cocultivation of IL-3 dependent hematopoietic progenitor cell line FDC-P1JL26 with 5000 cGy irradiated clonal bone marrow stromal cell line D2XRII has been demonstrated to stimulate selection of factor indepen...

    J. S. Greenberger, J. Lief, P. Anklesaria… in Neoplastic Transformation in Human Cell Cu… (1991)

  3. Article

    Gene therapy for radiation protection

    J S Greenberger in Gene Therapy (1999)

    Download PDF (119 KB) View Article

  4. No Access

    Article

    Cell phenotype specific kinetics of expression of intratracheally injected manganese superoxide dismutase–plasmid/liposomes (MnSOD–PL) during lung radioprotective gene therapy

    Intratracheal (IT) injection of manganese superoxide dismutase–plasmid/liposome (MnSOD-PL) complexes prior to whole lung irradiation of C57BL/6J mice provides significant protection from acute and chronic irra...

    M W Epperly, H L Guo, M Jefferson, S Nie, J Gretton, M Bernarding… in Gene Therapy (2003)

  5. No Access

    Article

    Inhalation delivery of manganese superoxide dismutase-plasmid/liposomes protects the murine lung from irradiation damage

    Intratracheal injection of manganese superoxide dismutase-plasmid/liposome (MnSOD-PL) complexes has been demonstrated to delay the onset and reduce the extent of ionizing irradiation-induced murine pulmonary o...

    M Carpenter, M W Epperly, A Agarwal, S Nie, L Hricisak, Y Niu… in Gene Therapy (2005)

  6. No Access

    Article

    Gene therapy approaches for stem cell protection

    Cytotoxic exposure of bone marrow and other non-hematopoietic organs containing self-renewing stem cell populations is associated with damage to the supportive microenvironment. Recent evidence indicates that ...

    J S Greenberger in Gene Therapy (2008)

  7. No Access

    Article

    Intraesophageal MnSOD-plasmid liposome enhances engraftment and self-renewal of bone marrow derived progenitors of esophageal squamous epithelium

    We evaluated whether the improved esophageal radiation tolerance following Manganese Superoxide Dismutase (MnSOD)-Plasmid Liposomes was explained by improved engraftment of bone marrow-derived progenitors. C57...

    Y Niu, M W Epperly, H Shen, T Smith, H Wang, J S Greenberger in Gene Therapy (2008)

  8. No Access

    Article

    Methyltransferases mediate cell memory of a genotoxic insult

    Characterization of the direct effects of DNA-damaging agents shows how DNA lesions lead to specific mutations. Yet, serum from Hiroshima survivors, Chernobyl liquidators and radiotherapy patients can induce a...

    R E Rugo, J T Mutamba, K N Mohan, T Yee, J R Chaillet, J S Greenberger… in Oncogene (2011)

  9. No Access

    Article

    Modulation of in utero total body irradiation induced newborn mouse growth retardation by maternal manganese superoxide dismutase-plasmid liposome (MnSOD-PL) gene therapy

    To determine the effects of manganese superoxide dismutase (MnSOD) plasmid liposome (PL) maternal radioprotection on fetal mice, timed pregnant female mice (E14 gestation) were irradiated to 3.0 Gy total body ...

    M W Epperly, T Smith, X Zhang, J P Goff, D Franicola, B Greenberger… in Gene Therapy (2011)