Overview
- Editors:
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Johng S. Rhim
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Laboratory of Cellular and Molecular Biology, National Cancer Institute, Bethesda, USA
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Anatoly Dritschilo
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Department of Radiation Medicine, Georgetown University Medical Center, USA
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About this book
The role of carcinogenic agents in the deveolopment of human cancers is now being defined using a variety of human cells as experi mental model systems. A workshop on "neoplastic transformation in human cell systems in vitro: mechanisms of carcinogenesis" was held at the Georgetown University Medical Center, Washington, DC, on April 25-26, 1991. The aims of the workshop were to present the state-of-the art in the transformation of human cells in culture, as well as to provide insight into the molecular and cellular changes involved in the conver sion of normal cells to a neoplastic state of growth. The following topics were closely related to the theme of the workshops: 1. Derivation of in vitro model systems (epithelial, fibroblastic, and hematopoietic). 2. Factors modulating cellular transformation. 3. Usefulness of defined in vitro model systems for viral, chemical, and radiation carcinogenesis. 4. Multistep nature of human cell carcinogenesis. 5. Role of activated and suppressor oncogenes in neoplastic trans formation. The workshop was organized by J. S. Rhim and A. Dritschilo (cochairmen), G. Jay, J. little, M. McCormick, R Tennant, and R R Weischelbaum. There were 32 speakers, 30 poster presentations, and about 190 participants.
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Article
01 September 2019
Table of contents (38 chapters)
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Front Matter
Pages i-xxxi
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Preneoplastic Events
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- K. K. Sanford, R. Parshad
Pages 15-23
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- B. Lynn Allen-Hoffmann, Nader Sheibani, Jill S. Hatfield, Johng S. Rhim
Pages 25-34
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- William E. Fahl, William H. Brondyk, Hua-Ming **, Craig W. Stevens, Carsten-Peter Carstens, Gregory C. Kujoth et al.
Pages 35-46
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- C. Chandra Kumar, Cecile Chang, Johng Rhim
Pages 47-56
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- S. Beninati, S. C. Park, M. Piacentini, J. S. Rhim, S. I. Chung
Pages 57-64
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Radiation Transformation and Oncogenes
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- J. B. Little, L.-N. Su, Y. Kano
Pages 67-79
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- Dennis E. Hallahan, Matthew L. Sherman, Donald Kufe, Ralph R. Weichselbaum
Pages 81-92
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- P. Thraves, S. Reynolds, Z. Salehi, W. K. Kim, J. H. Yang, J. S. Rhim et al.
Pages 93-101
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- T. C. Yang, M. R. Stampfer, J. S. Rhim
Pages 103-111
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- James C. Willey, Jim Greene, Alberec Bressoud, Peter Cerutti, Tom Hei, Nancy Wang et al.
Pages 113-117
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- J. S. Greenberger, J. Lief, P. Anklesaria, M. A. Sakakeeny, D. English, D. Crawford et al.
Pages 119-123
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- S. Srivastava, Z. Zou, K. Pirollo, D. Tong, V. Sykes, K. Devadas et al.
Pages 125-134
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- M. Nagarajan, M. Bowman, L. Rigby, J. S. Rhim, S. Sukumar
Pages 135-139
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Viral Transformation and Oncogenes
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Front Matter
Pages 141-141
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- Jonathan A. Rhim, Jonathan Vogel, Chang-Min Kim, Gilbert Jay, Johng S. Rhim
Pages 143-152
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Reviews
...should be a part of any departmental library serving virologists, cell biologists, pathologists, and other scientists interested in malignant cell growth.-Quarterly Review of Biology
Editors and Affiliations
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Laboratory of Cellular and Molecular Biology, National Cancer Institute, Bethesda, USA
Johng S. Rhim
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Department of Radiation Medicine, Georgetown University Medical Center, USA
Anatoly Dritschilo