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Chapter
Distributed Ledger Technology in Industry 4.0: An Implementation
Blockchain, also known as distributed ledger technology, is a type of transformational technology that is currently regarded as one of the most important instruments Industry many properties, , decentrali...
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Article
Resistance to the Androgen Receptor Centred Therapies: Biology and Management
Prostate cancer is a changeling disease. Although majority of patients show clinical and biochemical responses for long periods of time to therapies targeting the androgen receptor (AR), a small percentage of ...
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Article
Open AccessAtezolizumab in locally advanced or metastatic urothelial cancer: a pooled analysis from the Spanish patients of the IMvigor 210 cohort 2 and 211 studies
The studies IMvigor 210 cohort 2 and IMvigor211 evaluated the efficacy of atezolizumab in patients with locally advanced or metastatic urothelial cancer (mUC) upon progression to platinum-based chemotherapy wo...
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Chapter and Conference Paper
A Model for the Strategic Management of Innovation and R&D Based on Real Options Valuation: Assessing the Options to Abandon and Expand Clinical Trials in Pharmaceutical Firms
In this short research paper, we conceptually propose a valuation model that is suitable for assessing R&D projects and managing uncertainty in pharmaceutical laboratories. Taking this into consideration, this...
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Article
Latest progress in molecular biology and treatment in genitourinary tumours
The management of genitourinary cancer, including bladder, prostate, renal and testicular cancer, has evolved dramatically in recent years due to a better understanding of tumour genetic mutations, alterations...
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Article
Correction to: SEOM Clinical Guideline for treatment of muscle-invasive and metastatic urothelial bladder cancer (2016)
Due to a technical issue, the family name of the author
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Article
Correction to: Persistent major alopecia following adjuvant docetaxel for breast cancer: incidence, characteristics, and prevention with scalp cooling
In the original publication of the article, Table 1 was published with incorrect caption and values. The Table 1 with corrected caption and values is given in this Correction.
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Article
Open AccessPersistent major alopecia following adjuvant docetaxel for breast cancer: incidence, characteristics, and prevention with scalp cooling
Persistent alopecia (PA) after docetaxel has been recently described. The aim of our study is to establish the incidence and characteristics of PA following adjuvant docetaxel for breast cancer (BC) and to tes...
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Article
Erratum to: Equity, barriers and cancer disparities: study of the Spanish Society of Medical Oncology on the access to oncologic drugs in the Spanish Regions
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Article
Open AccessMedical oncology future plan of the Spanish Society of Medical Oncology: challenges and future needs of the Spanish oncologists
The SEOM Future Plan is aimed at identifying the main challenges, trends and needs of the medical oncology speciality over the next years, including potential oncologist workforce shortages, and proposing reco...
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Article
Open AccessEquity, barriers and cancer disparities: study of the Spanish Society of Medical Oncology on the access to oncologic drugs in the Spanish Regions
The Spanish Society of Medical Oncology (SEOM) has conducted a study on the access to oncologic drugs across the 17 Spanish Regions with the aim of identifying potential heterogeneities and making proposals fo...
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Article
Open AccessSEOM Clinical Guideline for treatment of muscle-invasive and metastatic urothelial bladder cancer (2016)
The goal of this article is to provide recommendations for the diagnosis and treatment of muscle-invasive and metastatic bladder cancer. The diagnosis of muscle-invasive bladder cancer is made by pathologic ev...
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Article
New advances in genitourinary cancer: evidence gathered in 2014
This review provides updated information published in 2014 regarding advances and major achievements in genitourinary cancer. Sections include the best in prostate cancer, renal cancer, bladder cancer, and ger...
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Article
A 50-gene signature is a novel scoring system for tumor-infiltrating immune cells with strong correlation with clinical outcome of stage I/II non-small cell lung cancer
To identify a novel system for scoring intratumoral immune response that can improve prognosis and therapy decisions in early stage non-small cell lung cancer (NSCLC).
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Article
Recommendations for radiological diagnosis and assessment of treatment response in lung cancer: a national consensus statement by the Spanish Society of Medical Radiology and the Spanish Society of Medical Oncology
The last decade has seen substantial progress in the diagnostic and therapeutic approach to lung cancer, thus meaning that its prognosis has improved. The Spanish Society of Medical Radiology and the Spanish S...
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Article
Open AccessSEOM clinical guidelines for the treatment of renal cell carcinoma
The purpose of this article was to provide updated recommendations for the diagnosis and treatment of renal cell carcinoma. Pathological confirmation is mandatory before treatment with ablative or focal therap...
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Article
Zoledronic acid in genitourinary cancer
Bone metastases are a common complication of advanced prostate cancer and while they are less common in non-prostate genitourinary (GU) malignances, they have been reported in up to 35 % of patients with advan...
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Article
Genomic predictors of response to doxorubicin versus docetaxel in primary breast cancer
Taxanes and anthracyclines improve the outcome of early breast cancer, although the benefit is limited to a small proportion of patients and are toxic. We prospectively looked for predictors of response to the...
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Article
35th Annual Meeting of the European Association for the Study of Diabetes
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Article
Glutathione andγ -glutamyl cycle enzymes in rat mammary gland
The main enzymes of theγ-glutamyl cycle during the lactogenic cycle in rat mammary gland were studied. A significant increase was found in all of them with the onset of lactogenesis. The effect of methionine sulf...
