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Article
Measurement of histamine metabolites in brain and cerebrospinal fluid provides insights into histaminergic activity
Measurements of the concentrations of histamine's metabolites,tele-methylhistamine (t-MH) andtele-methylimidazoleacetic acid (t-MIAA), in brain have been used to evaluate histamine turnover in brains of animals, ...
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Munich Consensus Development Conference on Histamine Determination
The rapid development of modern technologies and the functional excellence of new equipment have offered much scope for the production of a whole battery of principally novel or modified assays for histamine d...
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Chapter
Measurement of Histamine Metabolites
Affirming the usefulness of measuring the metabolites is not to deny the usefulness of measuring histamine itself. Its measurement alone has yielded a wealth of information on its role in, and contribution to, sy...
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Article
Rostral-caudal concentration gradients of histamine metabolites in human cerebrospinal fluid
The metabolites of histamine,tele-methylhistamine (t-MH) andtele-methylimidazoleacetic acid (t-MIAA), have a large concentration gradient between cisternal and lumbar CSF in the rhesus monkey. The possibility of ...
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Article
Diurnal fluctuation in levels of histamine metabolites in cerebrospinal fluid of rhesus monkey
In samples of ventricular cerebrospinal fluid (CSF) that were collected from a conscious, restrained rhesus monkey at intervals of 30–90 min, levels of the histamine metabolites,tele-methylhistamine (t-MH) andtel...
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Article
Aspects of histamine metabolism
Progress in learning the role of histamine in physiology and pathology has been impeded by difficulties in accurately measuring histamine and by the deficiencies of methods to measure its metabolites. The avai...
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Article
Measurement of tele-methylhistamine and histamine in human cerebrospinal fluid, urine, and plasma
A gas chromatographic-mass spectrometric method described by us to measure tele-methylhistamine (t-MH) in brain was used to measure t-MH in human cerebrospinal fluid (CSF), urine and plasma. The presence of t-...
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Article
Histamine and some of its metabolites in human body fluids
The concentrations of histamine, t-methylhistamine and t-methylimidazoleacetic acid were measured in human cerebrospinal fluid, plasma and urine, Especially noteworthy are the levels of histamine in cerebrospi...