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Article
Regulation of host colony activity by the social parasite Polistes semenowi
The productivity of social groups depends critically on effective regulation of work effort among group members. In social insect colonies, regulation of work may be decentralised or alternatively may be contr...
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Article
Cosmetics and Conflicting Fictions in Balzac's César Birotteau
Scoundrel or honesty incarnate? The problematic representation of César Birotteau has, for some time, been a center of debate for Balzac scholars. This essay examines the subversion of the textual logic in the...
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Article
Measurement of histamine metabolites in brain and cerebrospinal fluid provides insights into histaminergic activity
Measurements of the concentrations of histamine's metabolites,tele-methylhistamine (t-MH) andtele-methylimidazoleacetic acid (t-MIAA), in brain have been used to evaluate histamine turnover in brains of animals, ...
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Chapter
Stimulation of 5-HT3 Receptors Inhibits Release of Endogenous Noradrenaline from Hypothalamus
Exposure to 20 mM KCl elicited a Ca++-dependent release of endogenous NA (noradrenaline) from superfused rat hypothalamic slices. Two consecutive exposures, S1 and S2, respectively, produced NA release of similar...
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Chapter
Munich Consensus Development Conference on Histamine Determination
The rapid development of modern technologies and the functional excellence of new equipment have offered much scope for the production of a whole battery of principally novel or modified assays for histamine d...
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Chapter
Measurement of Histamine Metabolites
Affirming the usefulness of measuring the metabolites is not to deny the usefulness of measuring histamine itself. Its measurement alone has yielded a wealth of information on its role in, and contribution to, sy...
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Article
Rostral-caudal concentration gradients of histamine metabolites in human cerebrospinal fluid
The metabolites of histamine,tele-methylhistamine (t-MH) andtele-methylimidazoleacetic acid (t-MIAA), have a large concentration gradient between cisternal and lumbar CSF in the rhesus monkey. The possibility of ...
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Article
Diurnal fluctuation in levels of histamine metabolites in cerebrospinal fluid of rhesus monkey
In samples of ventricular cerebrospinal fluid (CSF) that were collected from a conscious, restrained rhesus monkey at intervals of 30–90 min, levels of the histamine metabolites,tele-methylhistamine (t-MH) andtel...
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Article
Aspects of histamine metabolism
Progress in learning the role of histamine in physiology and pathology has been impeded by difficulties in accurately measuring histamine and by the deficiencies of methods to measure its metabolites. The avai...
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Article
Measurement of tele-methylhistamine and histamine in human cerebrospinal fluid, urine, and plasma
A gas chromatographic-mass spectrometric method described by us to measure tele-methylhistamine (t-MH) in brain was used to measure t-MH in human cerebrospinal fluid (CSF), urine and plasma. The presence of t-...
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Article
Histamine and some of its metabolites in human body fluids
The concentrations of histamine, t-methylhistamine and t-methylimidazoleacetic acid were measured in human cerebrospinal fluid, plasma and urine, Especially noteworthy are the levels of histamine in cerebrospi...
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Article
Tricyclic antidepressant drugs block histamine H2 receptor in brain
THE observation that cyproheptadine is a competitive antagonist of the histamine H2 receptor linked to adenylate cyclase in brain1 suggested that the chemically similar tricyclic antidepressant drugs may also hav...
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Article
Familial dysautonomia
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Article
Presence of Imidazoleacetic Acid Riboside and Ribotide in Rat Tissues
THE products of histamine metabolism in vivo have been catalogued in investigations of the urine1,2, but relatively little work has been done on metabolites present in tissues. Since excreted metabolites reflect ...
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Article
Acetylcholine-releasing Material in Neural Tissues
WHILE examining cholinergic substances in sciatic nerve1, we noted that acetone extracts of nerve caused a slow contraction of the guinea pig ileum (Fig. 1A). Identical lipid extracts of brain had the same effect...
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Article
Differences in the Disposition of Endogenous and Exogenous Substances by Cells
DURING recent years, evidence has been accumulating that cells often may discriminate between a substance that they synthesize and the same substance that is preformed and assimilated from the environment. Thi...
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Article
Fractionation of Heparin on an Anion Exchanger
PREPARATIONS of heparin have been shown to be heterogeneous by a variety of techniques1,2, but no method is available for the fractionation of bulk quantities of heparin or of other sulphomucopolysaccharides. The...
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Article
Vitamine