Chromosomes Today
Proceedings of the Ninth International Chromosome Conference held in Marseille, France, 18–21 June 1986
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Article
Indications d’une étude méiotique dans l’infertilité masculine
L’indication d’une exploration méiotique est rarement posée au cours de l’investigation d’une infertilité masculine. Or un certain nombre de mutations qui affectent le déroulement de la spermatogenèse se manif...
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Article
Three dimensional reconstruction of human pachytene spermatocyte nuclei of a 17;21 reciprocal translocation carrier: study of XY-autosome relationships
A study of XY-autosome relationships at the pachytene stage in an infertile 17–21 reciprocal translocation carrier was undertaken by means of three dimensional reconstruction. Synaptonemal complexes and the se...
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Article
Infertility in human males with autosomal translocations: meiotic study of a 14;22 Robertsonian translocation
Pachytene analysis was undertaken in a male patient heterozygous for a 14q22q Robertsonian translocation. The relatively low rate of XY autosome association led us to examine the relationships existing between...
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Article
Differential associative behaviour of mitotic and meiotic acrocentric chromosomes
A comparative study of the association of mitotic acrocentric chromosomes and acrocentric bivalents at the pachytene stage shows that at least two factors can act in the associative behaviour of these chromoso...
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Article
The microtubular cytoskeleton and chromosomes of unfertilized human oocytes aged in vitro
To detect structural alterations in human oocytes that may give rise to predisposition to aneuploidy, unfertilized human oocytes from an IVF programme were processed for indirect anti-tubulin immunofluorescenc...
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Differential elongation of autosomal pachytene bivalents related to their DNA content in human spermatocytes
The establishment of the complete karyotype of human pachytene spermatocytes reveals differences in stretching of chromosomes between meiosis and mitosis. Bivalents or specific regions of bivalents which exhib...
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Pachytene analysis in a 17;21 reciprocal translocation carrier: role of the acrocentric chromosomes in male sterility
Pachytene analysis was undertaken in an infertile male, heterozygous for a 17;21 reciprocal translocation. The quadrivalent was identified by its configuration and chromomere pattern. A non-random association ...
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Book
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Article
Loop formation and synaptic adjustment in a human male heterozygous for two pericentric inversions
Pachytene analysis was undertaken in an infertile male heterozygous for two pericentric inversions of chromosomes 1 and 9. The synaptic behaviour of the bivalent 1 inversion was the most informative. Analysis ...
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Direct estimation of the non-disjunction rate at first meiotic division in the human male
Chromosomal analysis of 100 second metaphases from 19 men attending an infertility clinic for various reasons was carried out to estimate the rate of non-disjunction occurring at first meiotic division. Second...
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Synapsis and synaptic adjustment in an infertile human male heterozygous for a pericentric inversion in chromosome 1
Synapsis and “synaptic adjustment” were analyzed, using electron microscopy in silver stained surface microspreads of inversion-bearing spermatocytes, in an infertile human male with an inherited pericentric i...
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Complete pachytene chromomere karyotypes of human spermatocyte bivalents
Well-spread human pachytene spermatocyte bivalents were obtained allowing specific identification of each bivalent within its total complement according to its chromomere sequence combined with further stainin...
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Chapter
Abstracts of Selected Posters
The analysis of chromosomes of mouse embryos permits detection of transmitted chromosome damage. The protocol involves the treatment of one parent (usually the male) with a clastogen, recovery of embryos and p...
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Chapter
Presumed Impairment of the X Inactivation During Meiotic Prophase: A Common Phenomenon Causing Spermatogenic Breakdown in Various Cytogenetic Conditions
Balanced autosomal translocations aremore frequently observed in men attending an infertility clinics that in general population (1). The sterilizing effects of these autosomal translocations appear to disturb...
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Article
Effects of 9.4 GHz microwave exposure on meiosis in mice
Exposure to 9.4 GHz pulsed microwaves at low power densities for 1 h/day during 2 weeks induces in adult male Balb/c mice disturbances in meiosis, consisting in an increase of translocations and the appearance...
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Article
Pachytene map** of the C 9 and acrocentric bivalents in the human oocyte
Provisional maps are presented for all acrocentric bivalents and bivalent 9, according to their chromomere patterns at pachytene in the human oocyte. Each G band is subdivided into several sub-bands whose numb...
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Article
Meiosis of trisomy 21 in the human pachytene oocyte
Association modalities of the three 21 chromosomes were studied during pachytene in three trisomy 21 fetuses whose chromosomal constitution was identified following amniocentesis. — Three classes of images wer...
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Constitutive heterochromatin and micronucleoli in the human oocyte at the diplotene stage
In the diplotene stage of the human oocyte, the processes of elaboration of the nucleolar material are amplified. The principal nucleoli are more voluminous but therir relations with the secondary constriction...
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Identification of pachytene bivalents in human male meiosis using G-banding technique
G-banding of human pachytene bivalents is obtained using trypsin digestion. Each, of the 22 autosomal bivalents is clearly identified. Such an identification leads to construction of the human pachytene map. O...
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Nucleoli and chromosomes: Their relationships during the meiotic prophase of the human fetal oocyte
The number of nucleoli and the relations between them and chromosomes in the human fetal oöcyte have been investigated in this study. The differences existing between first oöcytes and spermatocytes have been ...
