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  1. Article

    Open Access

    Otoferlin gene editing in sheep via CRISPR-assisted ssODN-mediated Homology Directed Repair

    Different mutations of the OTOF gene, encoding for otoferlin protein expressed in the cochlear inner hair cells, induces a form of deafness that is the major cause of nonsyndromic recessive auditory neuropathy sp...

    A. Menchaca, P. C. dos Santos-Neto, M. Souza-Neves, F. Cuadro… in Scientific Reports (2020)

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  2. No Access

    Article

    Interleukin-10 produced by recombinant adenovirus prolongs survival of cardiac allografts in rats

    Interleukin-10 (IL-10) and interleukin-4 (IL-4), two Th2-derived cytokines, are molecules with anti-inflammatory and immunodeviating properties whose direct expression in allografts may prolong graft survival....

    A David, J Chétritt, C Guillot, L Tesson, J-M Heslan, M-C Cuturi… in Gene Therapy (2000)

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    Article

    A transient monocyte defective function in idiopathic nephrotic syndrome (Lipoid nephrosis)

    Alterations in phagocytosis have been studied in 25 patients with idiopathic nephrotic syndrome (INS). At the time of investigation all patients had normal renal function.

    A. Branellec, J. Laurent, J. M. Heslan, C. Bruneau… in International Urology and Nephrology (1988)

  4. No Access

    Chapter and Conference Paper

    Immunology and Coagulation in Nephrotic Syndrome

    It is now generally accepted that the central abnormality in the nephrotic syndrome, irrespective of etiology, is an increase in glomerular permeability to protein. The resulting proteinuria, if not compensate...

    A. M. Robson, L. Schlesinger, E. Rodriguez, P. Fodor, A. T. Sobel… in Paediatric Nephrology (1984)