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  1. Article

    Open Access

    Genetic effects influencing risk for major depressive disorder in China and Europe

    Major depressive disorder (MDD) is a common, complex psychiatric disorder and a leading cause of disability worldwide. Despite twin studies indicating its modest heritability (~30–40%), extensive heterogeneity...

    T B Bigdeli, S Ripke, R E Peterson, M Trzaskowski, S-A Bacanu… in Translational Psychiatry (2017)

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  2. Article

    Open Access

    SNP-based heritability estimates of the personality dimensions and polygenic prediction of both neuroticism and major depression: findings from CONVERGE

    Biometrical genetic studies suggest that the personality dimensions, including neuroticism, are moderately heritable (~0.4 to 0.6). Quantitative analyses that aggregate the effects of many common variants have...

    A R Docherty, A Moscati, R Peterson, A C Edwards, D E Adkins… in Translational Psychiatry (2016)

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  3. Article

    Open Access

    Meta-analysis indicates that common variants at the DISC1 locus are not associated with schizophrenia

    Several polymorphisms in the Disrupted-in-Schizophrenia-1 (DISC1) gene are reported to be associated with schizophrenia. However, to date, there has been little effort to evaluate the evidence for association sys...

    I Mathieson, M R Munafò, J Flint in Molecular Psychiatry (2012)

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  4. No Access

    Article

    Bias in genetic association studies and impact factor

    M R Munafò, G Stothart, J Flint in Molecular Psychiatry (2009)

  5. No Access

    Article

    A whole genome association study of neuroticism using DNA pooling

    We describe a multistage approach to identify single nucleotide polymorphisms (SNPs) associated with neuroticism, a personality trait that shares genetic determinants with major depression and anxiety disorder...

    S Shifman, A Bhomra, S Smiley, N R Wray, M R James, N G Martin… in Molecular Psychiatry (2008)

  6. No Access

    Article

    Chronic fluoxetine treatment alters behavior, but not adult hippocampal neurogenesis, in BALB/cJ mice

    G-J Huang, D Bannerman, J Flint in Molecular Psychiatry (2008)

  7. Article

    Erratum: Map** regulatory variants for the serotonin transporter gene based on allelic expression imbalance

    Correction to: Molecular Psychiatry (2007) 12: 421–422; doi:10.1038/sj.mp.4001952 Following publication of this article, the authors noted that an incorrect name appeared in the online corresponding author inf...

    J Martin, J Cleak, S A G Willis-Owen, J Flint, S Shifman in Molecular Psychiatry (2007)

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  8. No Access

    Article

    Map** regulatory variants for the serotonin transporter gene based on allelic expression imbalance

    J Martin, J Cleak, S A G Willis-Owen, J Flint, S Shifman in Molecular Psychiatry (2007)

  9. No Access

    Article

    Association of the DRD2 gene Taq1A polymorphism and alcoholism: a meta-analysis of case–control studies and evidence of publication bias

    We investigated the association of the dopamine D2 receptor (DRD2) Taq1A polymorphism and alcoholism, using meta-analytic techniques, and specifically undertook an investigation of possible publication bias. Pote...

    M R Munafò, I J Matheson, J Flint in Molecular Psychiatry (2007)

  10. Article

    Erratum: Association of the NRG1 gene and schizophrenia: a meta-analysis

    Correction to: Molecular Psychiatry (2006) 11, 539–546. doi:10.1038/sj.mp.4001817 Following the online publication of the above article, the authors noticed the following error: in the footnote to Table 2, ‘rs...

    M R Munafò, D L Thiselton, T G Clark, J Flint in Molecular Psychiatry (2006)

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  11. No Access

    Article

    Association of the NRG1 gene and schizophrenia: a meta-analysis

    We investigated the association of the NRG1 gene and schizophrenia using meta-analytic techniques, combining all published data while restricting our analysis to studies investigating the most commonly reported s...

    M R Munafò, D L Thiselton, T G Clark, J Flint in Molecular Psychiatry (2006)

  12. No Access

    Article

    DCNP1: a novel candidate gene for major depression

    S A G Willis-Owen, S Shifman, R R Copley, J Flint in Molecular Psychiatry (2006)

  13. No Access

    Article

    Promise and pitfalls in the meta-analysis of genetic association studies: a response to Sen and Schinka

    M R Munafò, T Clark, J Flint in Molecular Psychiatry (2005)

  14. No Access

    Article

    Lack of association of the COMT (Val158/108 Met) gene and schizophrenia: a meta-analysis of case–control studies

    There is strong evidence for a genetic contribution to schizophrenia, but the contribution of individual candidate genes remains uncertain. We attempted to replicate a recent meta-analysis that reported an ass...

    M R Munafò, L Bowes, T G Clark, J Flint in Molecular Psychiatry (2005)

  15. No Access

    Article

    Does measurement instrument moderate the association between the serotonin transporter gene and anxiety-related personality traits? A meta-analysis

    We attempted to replicate the findings of two recent meta-analyses that personality inventory moderates the association between the serotonin transporter gene and anxiety-related traits. A total of 24 studies ...

    M R Munafò, T Clark, J Flint in Molecular Psychiatry (2005)

  16. No Access

    Article

    Genetic Polymorphisms and Personality in Healthy Adults: A systematic review and meta-analysis

    A meta-analysis was conducted on studies reporting data on associations between candidate genes and human personality. Studies reporting data for psychiatric populations (including organic disease and substanc...

    M R Munafò, T G Clark, L R Moore, E Payne, R Walton, J Flint in Molecular Psychiatry (2003)