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Article
Attenuation of ketamine-induced impairment in verbal learning and memory in healthy volunteers by the AMPA receptor potentiator PF-04958242
There is a need to develop treatments for cognitive impairment associated with schizophrenia (CIAS). The significant role played by N-methyl-d-aspartate receptors (NMDARs) in both the pathophysiology of schizophr...
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Article
The impact of abdominal aortic aneurysm surgery on intensive care unit resources in an Irish tertiary centre
The potential impact of surgical service reconfiguration on intensive care unit (ICU) resources needs to be assessed.
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Article
Remote detection of magmatic water in Bullialdus Crater on the Moon
The remote detection of surface water indigenous to the Moon has proved difficult because of alternative sources, such as the solar wind. Spectroscopic observations of hydroxyl-bearing materials in Bullialdus ...
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Chapter and Conference Paper
Pre-vasospasm: early brain injury
Despite modern advances in surgery, subarachnoid haemorrhage (SAH) continues to carry high morbidity and mortality rates. The reasons for this are currently unclear. It is certain however that vasospasm is not...
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Chapter and Conference Paper
Inhibition of c-Jun N-terminal kinase pathway attenuates cerebral vasospasm after experimental subarachnoid hemorrhage through the suppression of apoptosis
Recent studies have demonstrated that apoptosis in cerebral arteries could play an essential role in cerebral vasospasm after subarachnoid hemorrhage (SAH) and that SP600125, an inhibitor of c-Jun N-terminal k...
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Chapter and Conference Paper
Apoptotic markers in vasospasm after an experimental subarachnoid haemorrhage
Vasospasm remains a leading cause of morbidity and mortality in relation to subarachnoid haemorrhage (SAH). This study examined the role of apoptosis in vasospasm at 24 and 72 h. The main proteins of the caspa...
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Article
Elevated BNP with normal systolic function in asymptomatic individuals at-risk for heart failure: a marker of diastolic dysfunction and clinical risk
B-type natriuretic peptide (BNP) is widely accepted in the evaluation of left ventricular systolic dysfunction and heart failure. However, little is known of the implications of elevated BNP levels in individu...
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Article
Short Term vs Long Term Dexamethasone Treatment: Effects on Rat Diaphragm Structure and Function
The effects of dexamethasone treatment duration (2.5 vs 10 weeks) on diaphragm myosin heavy chain isoforms, fiber types, and contractile characteristics were studied in male rats. Compared with ad libitum-fed...
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Article
Complement C4 types in coeliacs and controls
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Article
Royal Academy of Medicine in Ireland Section of Biological Sciences Proceedings of Winter Meeting held on Monday, 5th January, 1987
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Article
Serum galactosyltransferase isoenzyme patterns of cancer patients with liver involvement
The level of galactosyltransferase activity was measured in the serum of 220 patients with a variety of solid tumours. There was a significantly greater proportion of patients with elevated galactosyltransfera...
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Chapter
Intranasal Delivery of the Peptide, Salmon Calcitonin
Calcitonin is a polypeptide hormone normally secreted by the parafollicular cells of mammalian thyroid glands and by the ultimobronchial gland of birds and fish. The linear sequence of 32 amino acids found in ...
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Article
Epidural morphine for post-operative analgesia: Experience with ten cases
EPIDURAL morphine as a method of post-operative pain relief was used in 10 patients undergoing surgery on the upper genito-urinary tract. Analgesia was assessed by means of a 10 cm linear analogue scale, and t...
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Article
Partial lipodystrophy and renal disease
A case of partial lipodystrophy with membrano-proliferative glomerulonephritis of the dense deposit subtype is described. A review of the literature is presented witt special reference to complement studies.
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Article
Leptospirosis and renal failure —clinical experience over a one year period
LEPTOSPIROSIS is endemic in the community and is under-diagnosed because of mild infections and atypical presentations. Renal failure is thought to occur in 10 per cent of diagnosed cases.
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Article
668 FOOTPRINTING THE NEWBORN-COST EFFECTIVE?
Footprinting the newborn for identification is a routine procedure in most hospitals and mandatory by law in many states. We examined the quality of the footprints in full term infants in light of the cost.
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Article
A technique of liver transplantation in the pig
TWENTY-SIX orthotopic liver homotransplants were performed in pigs. A detailed account of the surgical technique is presented as well as observations on the intraoperative management of the recipient and the g...
