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    Article

    Selective toxicity of neocarzinostatin-monoclonal antibody conjugates to the antigen-bearing human melanoma cell line in vitro

    Monoclonal antibodies (IgG1) against high molecular weight antigen A-1-43 on human melanoma cell line A-375 were successfully linked to the anti-tumour protein neocarzinostatin (NCS) using the heterobifunctional ...

    G. Lüders, W. Köhnlein, C. Sorg, J. Brüggen in Cancer Immunology, Immunotherapy (1985)

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    Detection of phenotypic differences on human malignant melanoma lines and their variant sublines with monoclonal antibodies

    The hybridoma technique was used to generate monoclonal antibodies against a wide spectrum of melanoma-associated surface antigens. Mice were immunized against the human melanoma lines Mel A-375, SK Mel-25, an...

    J. Brüggen, C. Sorg in Cancer Immunology, Immunotherapy (1983)

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    Membrane associated antigens of human malignant melanoma V: Serological ty** of cell lines using antisera from nonhuman primates

    Antisera against various melanoma cell lines were raised in nonhuman primates (Cercopithecus aethiop.). After exhaustive absorption with AB Rh + red blood cells and pooled platelets from about 200 donors the sera...

    J. Brüggen, C. Sorg, E. Macher in Cancer Immunology, Immunotherapy (1978)

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    Article

    Membrane-associated antigens of human malignant melanoma IV: Changes in expression of antigens on cultured melanoma cells

    Established melanoma cell lines were cultured for one passage (approximately 1 week) in different lots of fetal calf and new born calf sera and then tested against a panel of previously positively reacting ser...

    C. Sorg, J. Brüggen, Edelgard Seibert, E. Macher in Cancer Immunology, Immunotherapy (1978)