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Article
Selective toxicity of neocarzinostatin-monoclonal antibody conjugates to the antigen-bearing human melanoma cell line in vitro
Monoclonal antibodies (IgG1) against high molecular weight antigen A-1-43 on human melanoma cell line A-375 were successfully linked to the anti-tumour protein neocarzinostatin (NCS) using the heterobifunctional ...
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Article
Detection of phenotypic differences on human malignant melanoma lines and their variant sublines with monoclonal antibodies
The hybridoma technique was used to generate monoclonal antibodies against a wide spectrum of melanoma-associated surface antigens. Mice were immunized against the human melanoma lines Mel A-375, SK Mel-25, an...
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Article
Membrane associated antigens of human malignant melanoma V: Serological ty** of cell lines using antisera from nonhuman primates
Antisera against various melanoma cell lines were raised in nonhuman primates (Cercopithecus aethiop.). After exhaustive absorption with AB Rh + red blood cells and pooled platelets from about 200 donors the sera...
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Article
Membrane-associated antigens of human malignant melanoma IV: Changes in expression of antigens on cultured melanoma cells
Established melanoma cell lines were cultured for one passage (approximately 1 week) in different lots of fetal calf and new born calf sera and then tested against a panel of previously positively reacting ser...