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MC3R links nutritional state to childhood growth and the timing of puberty
The state of somatic energy stores in metazoans is communicated to the brain, which regulates key aspects of behaviour, growth, nutrient partitioning and development1. The central melanocortin system acts through...
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Article
The mechanisms of weight loss after bariatric surgery
Studies of lifestyle advice and dietary intervention show that although moderate, clinically significant weight loss is achievable and results in concomitant improvements in comorbidities, it is invariably tra...