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  1. No Access

    Article

    Transpupillary thermotherapy (TTT) by infrared irradiation of choroidal melanoma

    We studied the destructive effect of hyperthermia at sub-photocoagulation level of 45–60 °C on melanomas. Optimal conditions for spreading of heat into tissue are a wavelength of 700–900 nm, a temperature of 4...

    Mrs. J. G. Journée-De Korver, J. A. Oosterhuis… in Documenta Ophthalmologica (1992)

  2. No Access

    Article

    Determination of basal tear turnover in insulin-dependent diabetes mellitus patients by fluorophotometry

    The tear turnover was determined by fluorophotometry in 25 insulin-dependent diabetes mellitus (IDDM) patients without retinopathy and 29 IDDM patients with (pre-)proliferative retinopathy. The results were co...

    Th. R. Stolwijk, J. A. van Best, H. H. P. J. Lemkes… in International Ophthalmology (1991)

  3. No Access

    Article

    Xenon arch photocoagulator used for transpupillary hyperthermia

    The technique of near-infrared irradiation to obtain tumour necrosis in experimental pigmented melanomas is described. The xenon arch photocoagulator was modified and adapted for hyperthermia treatment. The ad...

    J. G. Journée-De Korver, J. A. Oosterhuis, J. A. Van Best… in Documenta Ophthalmologica (1991)

  4. No Access

    Chapter

    A large family with a dominant cone dystrophy revealing prodromally a severe tritan defect

    A Dutch family with an autosomal dominant cone dystrophy was followed over 7 generations. The index case was a 26 year old woman with subjective visual complaints, a mildly impaired visual acuity (0.9) and pra...

    L. N. Went, J. A. Oosterhuis, M. Van Schooneveld in Colour Vision Deficiencies X (1991)

  5. No Access

    Chapter

    Acoustospectrography and histology of intraocular Greene’s melanoma

    This study has been performed to investigate the potentials of acoustospectrographic analysis for the characterization of biological tissues in general and of intraocular tumours in particular. The animal mode...

    J. M. Thijssen, R. L. Romijn, J. L. van Delft… in Ultrasonography in Ophthalmology 12 (1990)

  6. No Access

    Article

    Effects of microwave-induced hyperthermia on the anterior segment of healthy rabbit eyes

    Hyperthermia was induced in nine healthy rabbit eyes by means of a microwave 2450 MHz stripline applicator. The anterior segment of each eye was heated to a fixed temperature of between 42° C and 46° C for 30 ...

    J. G. Bollemeijer, J. J. W. Lagendijk… in Graefe's Archive for Clinical and Experime… (1989)

  7. No Access

    Article

    Blood retinal and blood aqueous barriers in diabetics by fluorophotometry

    The permeability of the blood retinal barrier (PBRB) and the diffusion coefficient into the anterior chamber (kd) in 20 insulin dependent (ID) and in 11 non-insulin dependent (NID) diabetics with various degrees ...

    J. P. Boot, J. M. A. Van Gerven, J. A. Van Best Ph.D., L. Vrij… in Documenta Ophthalmologica (1989)

  8. No Access

    Article

    The effect of therapeutic ultrasound on the average of multiple intraocular pressures throughout the day in therapy-resistant glaucoma

    The effect of therapeutic ultrasound was evaluated in 17 patients with therapy-resistant glaucoma by comparing average intraocular pressure (IOP) curves measured before and 3–4 months after insonification. The...

    C. C. Sterk, P. H. M. v.d. Valk… in Graefe's Archive for Clinical and Experime… (1989)

  9. No Access

    Article

    Spontaneous retinal haemorrhages

    Five patients are described with spontaneous retinal haemorrhages. In two patients small retinal haemorrhages occurred at the posterior pole, in one of them after physical exertion. In three patients multiple ...

    J. A. Oosterhuis in Documenta Ophthalmologica (1988)

  10. No Access

    Article

    Early morphological changes induced by photodynamic therapy in amelanotic greene melanoma implanted in the anterior eye chamber of rabbits

    Morphological changes induced by photodynamic therapy (PDT) in amelanotic Greene melanoma implanted in the anterior eye chamber of rabbits were followed up to 24 h after PDT to study the development of tissue ...

    N. A. P. Franken, G. F. J. M. Vrensen, J. L. Van Delft… in Lasers in Medical Science (1988)

  11. No Access

    Article

    Ocular and orbital metastasis of cutaneous melanomas

    Two patients with orbital metastasis from cutaneous melanoma are described. In one patient the metastatic tumour was located in the iris, in the other one it was located in the lateral rectus muscle. Only symp...

    J. A. Oosterhuis, R. J. W. de Keizer, D. de Wolff-Rouendaal… in International Ophthalmology (1987)

  12. No Access

    Article

    Plasma fluorescein decay determination during fluorophotometry

    Two useful methods for determination of the decay curve of non-protein bound fluorescein (NPBF) in plasma up to 1 hour after intravenous fluorescein injection are described and evaluated. The course of NPBF is...

    J. P. Boot, J. A. Van Best, E. W. S. J. T** A Tsoi… in Documenta Ophthalmologica (1987)

  13. No Access

    Chapter

    Intraocular causes of diplopia

    A number of intraocular disturbances and diseases may cause diplopia.

    J. A. Oosterhuis in Eye Movement Disorders (1987)

  14. No Access

    Article

    Pigmented paravenous retinochoroidal atrophy (PPRA)

    Five patients with paravenous pigmented retinochoroidal atrophy (PPRA) are described. Signs of active uveitis and progression of the fundus lesions were observed in one patient. An inflammatory origin of this ...

    F. M. R. J. Haustrate, J. A. Oosterhuis in Documenta Ophthalmologica (1986)

  15. No Access

    Article

    Potential radiopharmaceuticals for the detection of ocular melanoma

    The uptake and distribution of several 4-(substituted amino)-iodoquinolines, 131I-labelled, and of 67Ga-citrate were investigated in Syrian golden hamsters with Greene melanomas. Because of its uptake in the mela...

    A. van Langevelde, C. N. M. Bakker, H. Boer… in European Journal of Nuclear Medicine (1986)

  16. No Access

    Article

    Enzyme activities in the rabbit cornea during immunogenic keratitis

    In rabbits inflammation of the cornea was induced by intrastromal injection of horse serum. Between 2 and 4 weeks after injection, infiltration of the cornea with leukocytes and neovascularization could be obs...

    N. J. van Haeringen, A. Bolkova… in Graefe's Archive for Clinical and Experime… (1986)

  17. No Access

    Chapter

    Iodine Labelled 5-Iodo-2-Thiouracil as a Melanoma Seeking Agent: A Potential Drug for Diagnosis and Treatment

    Adequate treatment of malignant melanoma places medical science before a difficult problem. Disseminated melanomas have poor prognoses. Moreover malignant melanomas are known to be radioresistant to a high deg...

    J. van der Plas, A. van Langevelde, J. A. Oosterhuis… in Progress in Radiopharmacy (1986)

  18. No Access

    Article

    Association of birdshot retinochoroidopathy and HLA-A29 antigen

    We tested the association of birdshot retinochoroidopathy and the HLA-A29 antigen. We could confirm a high association, as found by Nussenblatt et al. in 1982.

    G. S. Baarsma M.D., A. Kijlstra, J. A. Oosterhuis, P. J. Kruit… in Documenta Ophthalmologica (1986)

  19. No Access

    Article

    Abstracts of papers pharmacological meeting

    J. J. Beckorinqh, C. Korstanje, P. A. van Zwieten… in Pharmaceutisch Weekblad (1985)

  20. No Access

    Chapter and Conference Paper

    Acyclovir Treatment in Stromal Herperic Keratitis

    Acyclovir (Zovirax R) is an acyclic nucleoside possessing pronounced inhibitory activity against herpes simplex and varicella zoster virus. Contrary to other antiviral drugs topical instillation of acyclovir in t...

    R. Van Ganswijk, J. A. Oosterhuis, J. Versteeg in Herpetic Eye Diseases (1985)

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