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Article
Open AccessWhole-body [18F]-FDG-PET/MRI for staging of pediatric non-Hodgkin lymphoma: first results from a single-center evaluation
In 2015, the revised International Pediatric Non-Hodgkin Lymphoma Staging System was published. It mentions [18F]-FDG-PET/MRI as the latest method to perform whole-body imaging. However, supporting data are pendi...
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Article
Allogeneic hematopoietic SCT for alpha-mannosidosis: an analysis of 17 patients
Alpha-mannosidosis is a rare lysosomal storage disease. Hematopoietic SCT (HSCT) is usually recommended as a therapeutic option though reports are anecdotal to date. This retrospective multi institutional anal...
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Article
Successful autologous bone marrow rescue in patients who failed peripheral blood stem cell mobilization
We assessed autologous bone marrow (BM) harvest and hematologic recovery after high-dose chemotherapy (HDCT) in patients who failed to achieve peripheral blood stem cell (PBSC) mobilization. One hundred and n...
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Article
Spontaneous overexpression of the long form of the Bcl-X protein in a highly resistant P388 leukaemia
A novel resistant variant of murine P388 leukaemia, P388/SPR, was identified by de novo resistance to doxorubicin (DOX) in vivo. This mutant displayed a similar level of cross-resistance to etoposide (VP-16) a...
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Article
Differential single- versus double-strand DNA breakage produced by doxorubicin and its morpholinyl analogues
The morpholinyl analogues of doxorubicin (DOX) have previously been reported to be non-cross-resistant in multidrug resistant (MDR) cells due to a lower affinity for P-glycoprotein relative to the parent comp...
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Article
Cytokines and pancreatic cancer
Ten xenotransplants of human gastrointestinal carcinomas (eight human pancreatic carcinomas) were assayed for their sensitivity to human rIFN-7 and human rTNF-a in nude mice. Both substances demonstrated a dos...
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Article
Cytokines and pancreatic cancer the effect of rIFN-γ, HuLelFN, rTNF-α, and LAK-cells on pancreatic and other gastrointestinal tumors in vitro
A panel of 10 digestive tract carcinoma cell lines (6 pancreatic carcinomas) was assayed for their sensitivity to HuLelFN, human rIFN-7, rTNF-a and allogeneic human LAK-cells in vitro. In addition, a combinati...