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    Spontaneous overexpression of the long form of the Bcl-X protein in a highly resistant P388 leukaemia

    A novel resistant variant of murine P388 leukaemia, P388/SPR, was identified by de novo resistance to doxorubicin (DOX) in vivo. This mutant displayed a similar level of cross-resistance to etoposide (VP-16) a...

    J-S Kühl, S Krajewski, GE Durán, JC Reed, BI Sikic in British Journal of Cancer (1997)