-
Article
Correction: CUL4B promotes gastric cancer invasion and metastasis-involvement of upregulation of HER2
-
Chapter and Conference Paper
Mixing Characteristics of a Flap** Jet of Self-Excitation Due to a Flexible Film
This study investigates a new type of turbulent flap** jets ‘self-excited’ through a thin FEP film fixed the jet nozzle exit by measuring their mixing characteristics. The study is conducted with varying fil...
-
Chapter and Conference Paper
Numerical Simulations on Film Cooling Effectiveness from Two Staggered Rows of Coolant Jets
This paper reports numerical simulations of the film cooling performance and flow structure from two staggered rows of coolant jets. The RANS modeling is conducted for the cases that are validated by and match...
-
Chapter and Conference Paper
Quantitative Investigation on the Formation of Counter-Rotating Vortex Pairs from the Inclined Jet in Crossflow
This study investigates by LES the formation and evolution of counter-rotating vortex pair (CRVP) from a streamwise-inclined 35° turbulent jet in a laminar crossflow (JICF). A new method is developed by which ...
-
Article
CUL4B promotes gastric cancer invasion and metastasis-involvement of upregulation of HER2
Cullin 4B (CUL4B) is a scaffold protein overexpressed in several solid malignancies. It is known to silence tumor suppressor through post-transcriptional manner. However, its clinical significance and underlyi...
-
Article
Open AccessDesign and Characterisation of Metallic Glassy Alloys of High Neutron Shielding Capability
This paper reports the design, making and characterisation of a series of Fe-based bulk metallic glass alloys with the aim of achieving the combined properties of high neutron absorption capability and suffici...
-
Chapter and Conference Paper
Formation and Evolution of the Flow Structure of an Inclined Jet in Crossflow
Large-eddy simulation (LES) was used to investigate the formation and evolution of the flow structure of a streamwise-inclined 35° turbulent jet in crossflow (JICF). Predictions by LES agree well with the expe...
-
Chapter and Conference Paper
Influence of Blowing Ratio on Flow Structures of an Inclined Jet in Crossflow
This study investigates by experiment the influence of the blowing ratio (BR) on the flow structures of an inclined turbulent jet in crossflow (JICF). The experiment was conducted in a water tunnel with the jet i...
-
Article
Diffusion MILD Combustion of Firing Pulverized-coal at a Pilot Furnace
This paper presents the computational investigation of the diffusion MILD (Moderate or Intense Low-oxygen Dilution) combustion of firing pulverized-coal at a pilot furnace. Dependences of the combustion perfor...
-
Article
Hypertension outcomes in metabolically unhealthy normal-weight and metabolically healthy obese children and adolescents
Metabolically healthy obesity (MHO) begins in childhood and continues into adulthood. However, the association between MHO and the risk of develo** hypertension remains controversial. A prospective cohort st...
-
Article
Chemical Flame Length of a Methane Jet into Oxidant Stream
The present paper reports a systematic study on different methods of obtaining the chemical length of a turbulent non-premixed CH 4 jet flame. The study is performed based on numerical simulations by the RANS mod...
-
Article
Open AccessHypoxia-induced miR-424 decreases tumor sensitivity to chemotherapy by inhibiting apoptosis
Chemotherapy resistance of tumor cells is a big challenge. Adaption to hypoxia is an essential cellular response that is controlled by the master oxygen-sensitive transcription factor HIF1 (hypoxia-inducible f...
-
Chapter and Conference Paper
Comparison of the Near-Field Flow Structures of a Triangular Jet with and without the Initial Confinement of a Chamber
This paper reports a large eddy simulation (LES) of the precession-like oscillation produced by partially confining a triangular-jet flow with a short cylindrical chamber. The present LES, which has been verif...
-
Article
Association of common variants in/near six genes (ATP2B1, CSK, MTHFR, CYP17A1, STK39 and FGF5) with blood pressure/hypertension risk in Chinese children
Recent genome-wide association studies have identified several single-nucleotide polymorphisms (SNPs) that are associated with blood pressure (BP)/hypertension. In this study, we aimed to examine the establish...
-
Chapter and Conference Paper
On Spectral Exponent Over Inertial Range in a Turbulent Square Jet
This paper reports a study that investigates the effects of the large-scale intermittency factor γ and the mean shear S on the inertial range spectral exponent m in the far field of a turbulent square jet (γ is d...
-
Article
Phase Field Simulation of Binary Alloy Dendrite Growth Under Thermal- and Forced-Flow Fields: An Implementation of the Parallel–Multigrid Approach
Dendrite growth and morphology evolution during solidification have been studied using a phase field model incorporating melt convection effects, which was solved using a robust and efficient parallel, multigr...
-
Article
Associations of obesity susceptibility loci with hypertension in Chinese children
Recent genome-wide association studies have identified several single-nucleotide polymorphisms (SNPs) that are associated with body mass index (BMI)/obesity.
-
Article
Open AccessValosin-containing protein regulates the proteasome-mediated degradation of DNA-PKcs in glioma cells
DNA-dependent protein kinase (DNA-PK) has an important role in the repair of DNA damage and regulates the radiation sensitivity of glioblastoma cells. The VCP (valosine-containing protein), a chaperone protein...
-
Article
A sex-specific effect of the CYP17A1 SNP rs11191548 on blood pressure in Chinese children
CYP17A1 gene encodes the cytochrome P450 enzyme CYP17A1, a key enzyme involved in steroid metabolism. A single nucleotide polymorphism (SNP) near CYP17A1, rs11191548, showed significant association with hypertens...
-
Article
Common polymorphism near the MC4R gene is associated with type 2 diabetes: data from a meta-analysis of 123,373 individuals
Genome-wide association studies have shown that variants near the melanocortin 4 receptor gene (MC4R) (rs17782313 and rs12970134) are associated with risk of obesity in Europeans. As obesity is associated with an...
