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Article
Small-molecule-induced Rho-inhibition: NSAIDs after spinal cord injury
Limited axonal plasticity within the central nervous system (CNS) is a major restriction for functional recovery after CNS injury. The small GTPase RhoA is a key molecule of the converging downstream cascade t...
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Article
Intrinsic locomotor outcome in dorsal transection of rat spinal cord: predictive value of minimal incision depth
Experimental, prospective, blinded, animal study.
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Article
A simple methodology to improve AIS-based assessment of recovery after acute spinal cord injury
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Article
Microglia rules: insights into micoglial–neuronal signaling
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Article
Long-term expression of heme oxygenase-1 (HO-1, HSP-32) following focal cerebral infarctions and traumatic brain injury in humans
Extracellular heme derived from hemoglobin following hemorrhage or released from dying cells induces the expression of heme oxygenase-1 (HO-1, HSP-32) which metabolizes heme to the gaseous mediator carbon mon...
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Article
Selective accumulation of cyclooxygenase-1-expressing microglial cells/macrophages in lesions of human focal cerebral ischemia
Cyclooxygenases (COX; prostaglandin endoperoxide H synthases) are key enzymes in the conversion of arachidonic acid into prostanoids which mediate inflammation, immunomodulation, mitogenesis, ovulation, fewer...