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    Article

    Small-molecule-induced Rho-inhibition: NSAIDs after spinal cord injury

    Limited axonal plasticity within the central nervous system (CNS) is a major restriction for functional recovery after CNS injury. The small GTPase RhoA is a key molecule of the converging downstream cascade t...

    M. A. Kopp, T. Liebscher, A. Niedeggen, S. Laufer, B. Brommer in Cell and Tissue Research (2012)

  2. Article

    Intrinsic locomotor outcome in dorsal transection of rat spinal cord: predictive value of minimal incision depth

    Experimental, prospective, blinded, animal study.

    K Brechtel, A Tura, M Abdibzadeh, S Hirsch, S Conrad, J M Schwab in Spinal Cord (2006)

  3. Article

    A simple methodology to improve AIS-based assessment of recovery after acute spinal cord injury

    R Jaeger, K Brechtel, H J Schluesener, S Conrad, H -P Kaps, J M Schwab in Spinal Cord (2005)

  4. Article

    Microglia rules: insights into micoglial–neuronal signaling

    J M Schwab, H J Schluesener in Cell Death & Differentiation (2004)

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    Article

    Long-term expression of heme oxygenase-1 (HO-1, HSP-32) following focal cerebral infarctions and traumatic brain injury in humans

    Extracellular heme derived from hemoglobin following hemorrhage or released from dying cells induces the expression of heme oxygenase-1 (HO-1, HSP-32) which metabolizes heme to the gaseous mediator carbon mon...

    R. Beschorner, D. Adjodah, J. M. Schwab, M. Mittelbronn, I. Pedal in Acta Neuropathologica (2000)

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    Article

    Selective accumulation of cyclooxygenase-1-expressing microglial cells/macrophages in lesions of human focal cerebral ischemia

    Cyclooxygenases (COX; prostaglandin endoperoxide H synthases) are key enzymes in the conversion of arachidonic acid into prostanoids which mediate inflammation, immunomodulation, mitogenesis, ovulation, fewer...

    J. M. Schwab, T. D. Nguyen, E. Postler, R. Meyermann in Acta Neuropathologica (2000)