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  1. No Access

    Article

    Translationally controlled tumor protein induces human breast epithelial cell transformation through the activation of Src

    Translationally controlled tumor protein (TCTP) is implicated in cell growth and malignant transformation. TCTP has been found to interact directly with the third cytoplasmic domain of the α subunit of Na,K-AT...

    J Jung, H Y Kim, M Kim, K Sohn, M Kim, K Lee in Oncogene (2011)

  2. No Access

    Article

    Inflammatory lipid sphingosine-1-phosphate upregulates C-reactive protein via C/EBPβ and potentiates breast cancer progression

    A crucial role of the inflammatory lipid sphingosine-1-phosphate (S1P) in breast cancer aggressiveness has been reported. Recent clinical studies have suggested that C-reactive protein (CRP) has a role in brea...

    E-S Kim, Y Cha, M Ham, J Jung, S G Kim, S Hwang, R Kleemann, A Moon in Oncogene (2014)

  3. No Access

    Article

    Synergistic activity and heterogeneous acquired resistance of combined MDM2 and MEK inhibition in KRAS mutant cancers

    There are currently no effective targeted therapies for KRAS mutant cancers. Therapeutic strategies that combine MEK inhibitors with agents that target apoptotic pathways may be a promising therapeutic approach. ...

    A N Hata, S Rowley, H L Archibald, M Gomez-Caraballo, F M Siddiqui, F Ji… in Oncogene (2017)

  4. No Access

    Article

    C-reactive protein binds to integrin α2 and Fcγ receptor I, leading to breast cell adhesion and breast cancer progression

    C-reactive protein (CRP) is an acute phase protein synthesized upon the inflammatory responses, associated with breast cancer. The process of tumor cell invasion and metastasis involves the adherence of cells ...

    E-S Kim, S Y Kim, M Koh, H-M Lee, K Kim, J Jung, H S Kim, W K Moon, S Hwang… in Oncogene (2018)