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  1. No Access

    Article

    Modeling BCR-ABL and MLL-AF9 leukemia in a human bone marrow-like scaffold-based xenograft model

    Although NOD-SCID IL2Rγ−/− (NSG) xenograft mice are currently the most frequently used model to study human leukemia in vivo, the absence of a human niche severely hampers faithful recapitulation of the disease. ...

    P Sontakke, M Carretta, J Jaques, A Z Brouwers-Vos, L Lubbers-Aalders, H Yuan… in Leukemia (2016)

  2. No Access

    Article

    CITED2-mediated human hematopoietic stem cell maintenance is critical for acute myeloid leukemia

    As the transcriptional coactivator CITED2 (CBP/p300-interacting-transactivator-with-an ED-rich-tail 2) can be overexpressed in acute myeloid leukemia (AML) cells, we analyzed the consequences of high CITED2 ex...

    P M Korthuis, G Berger, B Bakker, M Rozenveld-Geugien, J Jaques, G de Haan… in Leukemia (2015)

  3. No Access

    Article

    MLL–AF9-mediated immortalization of human hematopoietic cells along different lineages changes during ontogeny

    The MLL–AF9 fusion gene is associated with aggressive leukemias of both the myeloid and lymphoid lineage in infants, whereas in adults, this translocation is mainly associated with acute myeloid leukemia. Thes...

    S J Horton, J Jaques, C Woolthuis, J van Dijk, M Mesuraca, G Huls, G Morrone… in Leukemia (2013)

  4. No Access

    Article

    Lab lessons learned—part 3: Tire modal impact testing and forced-response analysis

    D. E. Adams, J. Jaques, M. Strus, A. Vyas, R. W. Bono in Experimental Techniques (2006)

  5. No Access

    Article

    Semiconductor Optical Amplifiers-Functional Applications

    In this paper we review functional applications of semiconductor optical amplifiers. For example, wavelength conversion, optical demultiplexing, and optical logic elements are discussed, which are attractive f...

    N. K. Dutta, Q. Wang, G. Zhu, J. Jaques, A. B. Piccirilli, J. Leuthold in Journal of Optics (2004)

  6. No Access

    Article

    Effect of leukemia inhibitory factor on hemopoietic and stromal precursor cells in prolonged culture of mouse bone marrow

    Treatment of prolonged bone marrow cultures with leukemia inhibitory factor during the first 2 weeks after explantation has no appreciable effect on the production of precursors and mature hemopoietic cells du...

    N. I. Drize, O. I. Gan, I. L. Chertkov… in Bulletin of Experimental Biology and Medic… (1996)