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  1. Article

    SOLTI (Solid Tumor Intensification) Group experience with high-dose chemotherapy treatment for early breast carcinoma

    H Cortés Funes, A Lluch, M Climent, JJ López, B Ojeda, J Hornedo… in Breast Cancer Research (2005)

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    Article

    Mobilization of peripheral blood progenitor cells with a combination of cyclophosphamide, r-metHuSCF and filgrastim in patients with breast cancer previously treated with chemotherapy

    The objective of our study was to determine the effect of adding r-metHuSCF to Filgrastim and cyclophosphamide for mobilization of peripheral blood progenitor cells (PBPC), on collection of CD34+ cells and engraf...

    F Prósper, C Solá, J Hornedo, C Arbona, P Menéndez, A Orfao, A Lluch… in Leukemia (2003)

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    Article

    The role of granulocyte colony-stimulating factor (G-CSF) in the post-transplant period

    The administration of G-CSF post transplant has been shown to accelerate the time to neutrophil engraftment. However, this does not necessarily translate into a meaningful clinical benefit to the patient. This...

    J Hornedo, C Solá, C Solano, JJ López, S Alonso, A Lluch… in Bone Marrow Transplantation (2002)

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    Article

    Sequential analysis of CD34+ and CD34− cell subsets in peripheral blood and leukapheresis products from breast cancer patients mobilized with SCF plus G-CSF and cyclophosphamide

    Administration of stem cell factor (SCF) has been proven to enhance cytokine-induced mobilization of CD34+ hematopoietic progenitor cells (HPC) into the peripheral blood (PB). The aim of the present study was to ...

    P Menéndez, F Prósper, C Bueno, C Arbona, JF San Miguel, J García-Conde, C Solá… in Leukemia (2001)

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    Article

    High-dose mitoxantrone and cyclophosphamide without stem cell support in high-risk and advanced solid tumors: a phase I trial

    This phase I study was designed to develop a high-dose combination of two cycles of mitoxantrone and cyclophosphamide in patients with solid tumors, as an alternative to single-cycle high-dose regimens that us...

    JL Pérez-Gracia, R Colomer, A Ruiz-Casado, A Arcediano… in Bone Marrow Transplantation (2001)

  6. Article

    Open Access

    Granulocyte colony-stimulating factor (G-CSF) transiently suppresses mitogen-stimulated T-cell proliferative response

    Granulocyte colony-stimulation factor (G-CSF) is a cytokine that selectively promotes growth and maturation of neutrophils and may modulate the cytokine response to inflammatory stimuli. The purpose of this st...

    E Reyes, I García-Castro, F Esquivel, J Hornedo… in British Journal of Cancer (1999)

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    Article

    Octreotide (SMS 201–995) for hematopoietic support-dependent high-dose chemotherapy (HSD-HDC)-related diarrhoea: dose finding study and evaluation of efficacy

    Emphasis has been put on the intensification of chemotherapy programs through high-dose chemotherapy regimens. While their myelosuppression is managed through the use of colony-stimulating factors and/or infus...

    EI Wasserman, M Hidalgo, J Hornedo, H Cortés-Funes in Bone Marrow Transplantation (1997)