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Article
Treatment for primary refractory Hodgkin's disease: a comparison of high-dose chemotherapy followed by ASCT with conventional therapy
Our previously published study showed promising results of autologous stem cell transplantation (ASCT) in patients with primary resistant Hodgkin's disease (HD). Probabilities of overall survival (OS) and prog...
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Article
Treatment-related mortality and graft-versus-leukemia activity after allogeneic stem cell transplantation for chronic lymphocytic leukemia using intensity-reduced conditioning
Allogeneic stem cell transplantation (SCT) using reduced-intensity conditioning (RIC) has potential to be a promising treatment of aggressive chronic lymphocytic leukemia (CLL). Since available clinical data o...
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Article
High-dose chemotherapy with autologous stem cell transplantation is an effective treatment of primary refractory Hodgkin's disease. Retrospective study of the Polish Lymphoma Research Group
We analysed the treatment outcome of primary refractory HD patients managed with high-dose chemotherapy and haematopoietic cell transplantation. Data of 65 adult patients who underwent HDC/ASCT in nine Polish ...
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Article
Hematopoietic stem cell transplantation for multiple sclerosis
Rationale Phase I/II studies of autologous hematopoietic stem cell transplantation (HSCT) for multiple sclerosis (MS) were initiated, based on results of experimental transplantation in animal mo...
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Chapter
Molecular Monitoring of Treatment Efficacy after Hematopoietic Stem Cell Transplantation in Chronic Myeloid Leukemia
The presence of the BCR/ABL gene in chronic myeloid leukemia (CML) allows the detection of residual leukemic cells on the molecular level by polymerase chain reaction (PCR). We studied 38 patients (pts) with C...
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Chapter
Dexa-BEAM with High-Dose Cytarabine and Autologous Bone Marrow Transplantation Are Highly Effective in Heavily Pretreated Poor-Prognosis Lymphoma Patients
The purpose of the study was to evaluate if a modification of Dexa-BEAM regimen by escalation of the dose of cytarabine might improve the treatment efficacy in poor-prognosis lymphoma patients (pts.). We asses...
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Chapter
Immunomagnetic Purging of Marrow and Peripheral Blood Progenitors for Autografting in Patients with Lymphoproliferative Disorders — Selection Efficacy and Engraftment
For the diminution of tumor cell contamination in the grafts of patients with acute lymphoblastic leukemia (ALL — 6), multiple myeloma (MM — 6) and non-Hodgkin’s lymphomas (NHL — 3), a negative immunomagnetic ...
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Chapter
Delayed Granulocyte Recovery and Suppressed Growth of Grafted CFU-GM If Allogeneic Marrow Cells Are Transplanted 48 h After the Completion of High-Dose Busulfan and Cyclophosphamide (BuCy2) Therapy
Many factors affect the hematopoietic reconstitution after allogeneic bone marrow transplantation (alloBMT). We evaluated the impact of the time of marrow cell infusion after BuCy2 therapy on the speed of engr...
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Chapter and Conference Paper
The Effect of ATRA (Roche) on Clinical and Laboratory Parameters in 36 APL Patients — Polish Multicenter Retrospective Analysis
Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia (AML). It is characterized by an arrest of differentiation at the promyelocytic stage. APL is consistently associated with tra...
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Article
Successful cryopreservation of suspension cells by encapsulation-dehydration
Cryopreservation of a Catharanthus cell suspension was performed after encapsulation in alginate beads. Encapsulated cells were precultured in sucrose-enriched medium for several days, dried over silica gel, and ...
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Article
Importance of actin cytoskeleton behaviour during preservation of carrot cell suspensions in liquid nitrogen
Conventional methods for preservation of suspended, highly vacuolated, plant cells in liquid nitrogen (LN) usually involve equilibration in molar concentrations of cryoprotective additives, followed by slow co...
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Article
Abstract
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Article
Granulocyte progenitors (CFU-D) in neutrophilic leukemoid reaction are hyporesponsive to macrophage-induced inhibition
The responsiveness of marrow granulocyte progenitors (CFU-D) to macrophage-derived stimulatory and inhibitory factors has been studied using diffusion chamber technique in 12 patients with neutrophilic leukemo...