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  1. No Access

    Article

    Sequential Value of Information for Subsurface Exploration Drilling

    Quantitative methods are needed for systematic decision-making during exploration for subsurface resources, but few methods exist that fully incorporate the interaction of geological, operational, and financia...

    T. Hall, C. Scheidt, L. Wang, Z. Yin, T. Mukerji, J. Caers in Natural Resources Research (2022)

  2. No Access

    Article

    Efficacy of Information in Mineral Exploration Drilling

    In mineral exploration, targets need to be confirmed by means of drilling. Such drilling is based on anomalies often detected in geochemical and/or geophysical exploration. Because drilling is costly and becau...

    J. Caers, C. Scheidt, Z. Yin, L. Wang, T. Mukerji, K. House in Natural Resources Research (2022)

  3. Article

    Open Access

    Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel

    Solitary plasmacytoma is an infrequent form of plasma cell dyscrasia that presents as a single mass of monoclonal plasma cells, located either extramedullary or intraosseous. In some patients, a bone marrow as...

    J. Caers, B. Paiva, E. Zamagni, X. Leleu, J. Bladé in Journal of Hematology & Oncology (2018)

  4. Article

    Open Access

    Prevention and management of adverse events of Novel agents in multiple myeloma: A consensus of the european myeloma network

    During the last few years, several new drugs have been introduced for treatment of patients with multiple myeloma, which have significantly improved treatment outcome. All of these novel substances differ at l...

    H Ludwig, M Delforge, T Facon, H Einsele, F Gay, P Moreau, H Avet-Loiseau in Leukemia (2017)

  5. Article

    Open Access

    Whole-body computed tomography versus conventional skeletal survey in patients with multiple myeloma: a study of the International Myeloma Working Group

    For decades, conventional skeletal survey (CSS) has been the standard imaging technique for multiple myeloma (MM). However, recently whole-body computed tomography (WBCT) has been implemented into the diagnost...

    J Hillengass, L A Moulopoulos, S Delorme, V Koutoulidis, J Mosebach in Blood Cancer Journal (2017)

  6. No Access

    Article

    Management of relapsed multiple myeloma: recommendations of the International Myeloma Working Group

    The prognosis for patients multiple myeloma (MM) has improved substantially over the past decade with the development of new, more effective chemotherapeutic agents and regimens that possess a high level of an...

    J Laubach, L Garderet, A Mahindra, G Gahrton, J Caers, O Sezer, P Voorhees in Leukemia (2016)

  7. No Access

    Article

    Imaging myeloma and related monoclonal plasma cell disorders using MRI, low-dose whole-body CT and FDG PET/CT

    The identification of bone lesions and extramedullary disease is crucial in the diagnosis of myeloma. Whole-body X-ray (WBXR) is considered the gold standard for the detection of myeloma bone lesions. Neverth...

    N. Withofs, C. Nanni, P. Simoni, S. Fanti, Y. Beguin in Clinical and Translational Imaging (2015)

  8. No Access

    Article

    Plasma cell leukemia: consensus statement on diagnostic requirements, response criteria and treatment recommendations by the International Myeloma Working Group

    Plasma cell leukemia (PCL) is a rare and aggressive variant of myeloma characterized by the presence of circulating plasma cells. It is classified as either primary PCL occurring at diagnosis or as secondary P...

    C Fernández de Larrea, R A Kyle, B G M Durie, H Ludwig, S Usmani, D H Vesole in Leukemia (2013)

  9. Article

    Open Access

    Antitumour and antiangiogenic effects of Aplidin® in the 5TMM syngeneic models of multiple myeloma

    Aplidin® is an antitumour drug, currently undergoing phase II evaluation in different haematological and solid tumours. In this study, we analysed the antimyeloma effects of Aplidin in the syngeneic 5T33MM model,...

    J Caers, E Menu, H De Raeve, D Lepage, E Van Valckenborgh in British Journal of Cancer (2008)

  10. No Access

    Article

    Neighboring adipocytes participate in the bone marrow microenvironment of multiple myeloma cells

    J Caers, S Deleu, Z Belaid, H De Raeve, E Van Valckenborgh, E De Bruyne in Leukemia (2007)

  11. No Access

    Article

    Endothelial cell-driven regulation of CD9 or motility-related protein-1 expression in multiple myeloma cells within the murine 5T33MM model and myeloma patients

    The cell surface expression of CD9, a glycoprotein of the tetraspanin family influencing several processes including cell motility and metastasis, inversely correlates with progression in several solid tumors....

    E De Bruyne, T L Andersen, H De Raeve, E Van Valckenborgh, J Caers, B Van Camp in Leukemia (2006)

  12. No Access

    Chapter and Conference Paper

    Multiple-point geostatistics: a powerful tool to improve groundwater flow and transport predictions in multi-modal formations

    L. Feyen, J. Caers in Geostatistics for Environmental Applications (2005)

  13. No Access

    Article

    Stochastic estimation of facies using ground penetrating radar data

    Explicitly defining large-scale heterogeneity is a necessary step of groundwater model calibration if accurate estimates of flow and transport are to be made. In this work, neural networks are used to estimate...

    S. Moysey, J. Caers, R. Knight in Stochastic Environmental Research and Risk… (2003)

  14. No Access

    Article

    Extreme value analysis of diamond-size distributions

    Extreme value analysis provides a semiparametric method for analyzing the extreme long tails of skew distributions which may be observed when handling mining data. The estimation of important tail characterist.....

    J. Caers, P. Vynckier, J. Beirlant, L. Rombouts in Mathematical Geology (1996)