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within J Barbazán Remove this filter Medicine & Public Health Remove this filter Internal Medicine Remove this filter

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    Article

    Conjugation of SUMO to p85 leads to a novel mechanism of PI3K regulation

    Class IA phosphatidylinositol 3-kinases (PI3Ks) are composed of p110 catalytic and p85 regulatory subunits. How regulatory subunits modulate PI3K activity remains only partially understood. Here we identified ...

    C F de la Cruz-Herrera, M Baz-Martínez, V Lang, A El Motiam, J Barbazán… in Oncogene (2016)