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Article
Open AccessAssessment of the pathogen genomics landscape highlights disparities and challenges for effective AMR Surveillance and outbreak response in the East African community
The East African Community (EAC) grapples with many challenges in tackling infectious disease threats and antimicrobial resistance (AMR), underscoring the importance of regional and robust pathogen genomics ca...
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Article
Open AccessAntibiotic-Resistant Arcobacter spp. in commercial and smallholder farm animals in Asante Akim North Municipality, Ghana and Korogwe Town Council, Tanzania: a cross-sectional study
Arcobacter species are considered emerging foodborne pathogens that can potentially cause serious infections in animals and humans. This cross-sectional study determined the frequency of potentially pathogenic Ar...
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Article
Open AccessFemale genital schistosomiasis, human papilloma virus infection, and cervical cancer in rural Madagascar: a cross sectional study
Women’s health in resource-limited settings can benefit from the integrated management of high-burden diseases, such as female genital schistosomiasis (FGS) and human papilloma virus (HPV)-related cervical can...
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Article
Open AccessCarriage of ESBL-producing Klebsiella pneumoniae and Escherichia coli among children in rural Ghana: a cross-sectional study
Extended-spectrum beta-lactamase (ESBL)-producing Klebsiella pneumoniae (ESBL-KP) and Escherichia coli (ESBL-EC) present a high burden in both communities and healthcare sectors, leading to difficult-to-treat inf...
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Article
Open AccessWhat are the pathways between poverty and malaria in sub-Saharan Africa? A systematic review of mediation studies
Malaria remains a major burden in sub-Saharan Africa (SSA). While an association between poverty and malaria has been demonstrated, a clearer understanding of explicit mechanisms through which socioeconomic po...
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Article
Open AccessPrevalence and risk distribution of schistosomiasis among adults in Madagascar: a cross-sectional study
The goal to eliminate the parasitic disease of poverty schistosomiasis as a public health problem is aligned with the 2030 United Nations agenda for sustainable development goals, including universal health co...
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Article
Open AccessPathogens associated with hospitalization due to acute lower respiratory tract infections in children in rural Ghana: a case–control study
Respiratory infections are one of the most common causes of death among children under the age of five years. Data on prevalence and relevance of specific organisms in African children are still lacking. This ...
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Article
Open AccessThe person-to-person transmission landscape of the gut and oral microbiomes
The human microbiome is an integral component of the human body and a co-determinant of several health conditions1,2. However, the extent to which interpersonal relations shape the individual genetic makeup of th...
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Article
Open AccessHigh seroprevalence of SARS-CoV-2 in Burkina-Faso, Ghana and Madagascar in 2021: a population-based study
The current COVID-19 pandemic affects the entire world population and has serious health, economic and social consequences. Assessing the prevalence of COVID-19 through population-based serological surveys is ...
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Article
Open AccessClustering of Cryptosporidium species infections among sheep and cattle but not children in remote highland communities of Madagascar
The aim of this study was to identify local transmission patterns of Cryptosporidium spp. infections among livestock and humans in four extremely rural and remote highland communities in Madagascar.
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Article
Open AccessChallenges in the clinical development pathway for triple and multiple drug combinations in the treatment of uncomplicated falciparum malaria
The addition of a third anti-malarial drug matching the pharmacokinetic characteristics of the slowly eliminated partner drug in artemisinin-based combination therapy (ACT) has been proposed as new therapeutic...
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Chapter
Erratum zu: Deutscher Filmpreis goes Green! – Ein Nachhaltigkeits-Management-System für Veranstaltungen. Anforderungen mit Anleitung zur Anwendung
Der Vorname von Frau Gewitsch wurde auf Fenja korrigiert (sowohl in der Affiliation als auch im Autorentext).
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Chapter
Deutscher Filmpreis goes Green! – Ein Nachhaltigkeits-Management-System für Veranstaltungen. Anforderungen mit Anleitung zur Anwendung
Seit 2018 spielt Nachhaltigkeit auch für den deutschen Filmpreis eine immer größere Rolle. In diesem Kapitel wird detailliert beschrieben, wie der Weg zu einem nachhaltigen Event für diese glamouröse Veranstal...
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Article
Open AccessA cluster randomized controlled trial for assessing POC-CCA test based praziquantel treatment for schistosomiasis control in pregnant women and their young children: study protocol of the freeBILy clinical trial in Madagascar
Mass drug administration (MDA) of praziquantel is one of the main control measures against human schistosomiasis. Although there are claims for including pregnant women, infants and children under the age of 5...
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Article
Open AccessNegative SARS-CoV-2 PCR or rapid antigen test result and the subsequent risk of being infectious: a mathematical simulation study
A considerable proportion of SARS-CoV-2 transmission occurs from asymptomatic and pre-symptomatic cases. Therefore, different polymerase chain reaction (PCR)- or rapid antigen test (RAT)-based approaches are b...
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Article
Open AccessCommentary: mobile laboratories for SARS-CoV-2 diagnostics: what Europe could learn from the East African Community to assure trade in times of border closures
The emergence of SARS-CoV-2 mutants might lead to European border closures, which impact on trade and result in serious economic losses. In April 2020, similar border closures were observed during the first SA...
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Article
Open AccessExploring the use of web searches for risk communication during COVID-19 in Germany
Risk communication during pandemics is an element of utmost importance. Understanding the level of public attention—a prerequisite for effective communication—implicates expensive and time-consuming surveys. W...
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Article
Open AccessMolecular and epidemiologic characterization of the diphtheria outbreak in Venezuela
In 2016, Venezuela faced a large diphtheria outbreak that extended until 2019. Nasopharyngeal or oropharyngeal samples were prospectively collected from 51 suspected cases and retrospective data from 348 clini...
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Article
Open AccessClassification of invasive bloodstream infections and Plasmodium falciparum malaria using autoantibodies as biomarkers
A better understanding of disease-specific biomarker profiles during acute infections could guide the development of innovative diagnostic methods to differentiate between malaria and alternative causes of fev...
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Article
Open AccessA cross-sectional study on risk factors for infection with Parvovirus B19 and the association with anaemia in a febrile paediatric population in Ghana
Parvovirus B19 (B19V) occurs globally and can cause severe anaemia. The role of co-infections with Plasmodium falciparum (P. falciparum) has been controversially discussed. The study aimed to determine prevalence...
