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Article
Hollow screws: a diagnostic tool for intracranial empyema
Subdural (SDE) and epidural empyema (EDE) are life-threatening intracranial infections. They require immediate diagnosis and treatment. However, in some cases, magnet resonance imaging (MRI) is not able to con...
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Article
Frameless image-guided stereotaxy with real-time visual feedback for brain biopsy
Frame-based stereotaxy remains the “gold standard” for cerebral biopsies and functional neurosurgery though new frameless stereotactic systems are evolving continually. As the technique of frameless stereotaxy...
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Article
Nuclear β-catenin accumulation associates with epithelial morphogenesis in craniopharyngiomas
Activation of the Wnt/wingless signalling cascade is a key mechanism in developmental morphogenesis, whereas aberrant nuclear accumulation of β-catenin in adult tissues seems to be associated with neoplastic t...
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Article
Abundant hypermethylation of SOCS-1 in clinically silent pituitary adenomas
Janus kinase (JAK)/signal transducers and activators of transcription (STAT) cascade are required for cytokines, growth factors, G-proteins and hormones (growth hormone and prolactin). Gatekeepers in this path...
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Article
Common mutations of β-catenin in adamantinomatous craniopharyngiomas but not in other tumours originating from the sellar region
Dysregulation of the Wnt signalling pathway contributes to developmental abnormalities and carcinogenesis of solid tumours. Here, we examined β-catenin and adenomatous polyposis coli (APC) by mutational analysis ...
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Article
Reale Kosten der MRSA-Osteitis