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Article
Open AccessDifferential requirement of neutralizing antibodies and T cells on protective immunity to SARS-CoV-2 variants of concern
The current COVID-19 vaccines protect against severe disease, but are not effective in controlling replication of the Variants of Concern (VOCs). Here, we used the existing pre-clinical models of severe and mo...
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Article
Open AccessUptake of Plasmodium chabaudi hemozoin drives Kupffer cell death and fuels superinfections
Kupffer cells (KCs) are self-maintained tissue-resident macrophages that line liver sinusoids and play an important role on host defense. It has been demonstrated that upon infection or intense liver inflammat...
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Article
Open AccessSplenic differentiation and emergence of CCR5+CXCL9+CXCL10+ monocyte-derived dendritic cells in the brain during cerebral malaria
Dendritic cells have an important role in immune surveillance. After being exposed to microbial components, they migrate to secondary lymphoid organs and activate T lymphocytes. Here we show that during mouse ...
