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Article
Ureaplasma urealyticum-Induced Production of Proinflammatory Cytokines by Macrophages
Ureaplasma urealyticum is relatively common in the respiratory tract of very low birth weight infants and has been hypothesized to be involved in the development of chronic lung disease. The purpose of this study...
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Article
Adenosine A2A receptors mediate the inhibitory effect of adenosine on formyl-Met-Leu-Phe-stimulated respiratory burst in neutrophil leucocytes
Using the reverse transcription polymerase chain reaction (RT PCR) we found that human neutrophils express mRNA for both A2A and A2B adenosine receptors, and using selective adenosine receptor agonists and antago...
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Article
Functional characterization of adenosine A2 receptors in Jurkat cells and PC12 cells using adenosine receptor agonists
The effect of several adenosine analogues on cyclic AMP accumulation was examined in the rat phaeochromocytoma cell PC12 and in the human T-cell leukaemia cell Jurkat, selected as prototypes of cells predomina...
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Article
Effect of long term caffeine treatment on A1 and A2 adenosine receptor binding and on mRNA levels in rat brain
The effect of long-term oral treatment with caffeine on A1 and A2 receptors in the rat brain was studied. Caffeine was added to the drinking water and the animals were sacrificed after a 12 day treatment period. ...
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Article
Role of a pertussis toxin sensitive G-protein in mediating the effects of phorbol esters on receptor activated cyclic AMP accumulation in Jurkat cells
In the human T -cell line, Jurkat, the accumulation of cyclic AMP induced by adenosine is enhanced by tumor-promoting phorbol esters, whereas prostaglandin E2 receptor-stimulated cAMP accumulation is antagonized ...
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Chapter
Interactions between the Modulator Adenosine and Classical Transmitters
There is continuous formation of adenosine in all cells. Methyltransferase reactions lead to the formation of S-adenosyl-homocysteine, which is rapidly broken down to form adenosine. The rate of adenosine form...
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Chapter
Interactions between the Modulator Adenosine and Classical Transmitters
There is continuous formation of adenosine in all cells. Methyltransferase reactions lead to the formation of S-adenosylhomocysteine, which is rapidly broken down to form adenosine. The rate of adenosine forma...