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  1. Article

    Open Access

    BugSplit enables genome-resolved metagenomics through highly accurate taxonomic binning of metagenomic assemblies

    A large gap remains between sequencing a microbial community and characterizing all of the organisms inside of it. Here we develop a novel method to taxonomically bin metagenomic assemblies through alignment o...

    Induja Chandrakumar, Nick P. G. Gauthier, Cassidy Nelson… in Communications Biology (2022)

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    Article

    Genome-wide detection of tandem DNA repeats that are expanded in autism

    Tandem DNA repeats vary in the size and sequence of each unit (motif). When expanded, these tandem DNA repeats have been associated with more than 40 monogenic disorders1. Their involvement in disorders with comp...

    Brett Trost, Worrawat Engchuan, Charlotte M. Nguyen, Bhooma Thiruvahindrapuram… in Nature (2020)